Yes to both, and it's way fucking overdue. Anime has given us adaptations of Berserk, Parasyte, Monster... basically any seinen manga adaptation you can think of. Now where is my adaptation of Sandman (seriously, you could never do Sandman in live action, it's just not gonna happen), Mark Millar's Nemesis, hell, Watchmen? Even if you just made adaptations of western comics (excluding superhero stuff obviously) you'd have decades worth of sublime material to turn into animation. Bojack Horseman might actually be a pioneer in this, since I struggle to call season 3 a comedy anymore, and unlike South Park or Family Guy that occasionally flirt with dark themes, Bojack Horseman actually has lasting consequences. It's a testament to the stigmatization of animation in the western world when a tragedy story about a man's struggle with fading fame and alienating everyone around him still has to wear the skin of a Hollywood satire with animals instead of people and currraaaaayyyzy side plots and running gags. Take the comedy aspect out of Bojack Horseman, and you have Requiem for a Dream levels of dark tragedy hiding behind the pasta strainers and drug jokes.