No, not really. Not having sex even becomes a part of life as people get older. Men are no longer able to perform and the female body reaches a point where sex can become extremely uncomfortable for them. Granted, there is Viagra for men and things for women that can help extend that deadline, but for most people, there is eventually a stopping point.
They don't go crazy.
At a younger age, it's hormones that drive sex, it's all human nature. That's why it's so frequently sought after.
Companionship, however, as others have said, is what is so important. There are exceptions to everything, but the majority of people can become depressed or upset if they don't have someone to share their life with emotionally. The sex is just a nice, fun, and enjoyable bonus to being with someone you care about.
Having a one night stand will quell the sex urge for a bit, but it doesn't substitute for companionship.