What would I do? Well, starting with realism, stem cells and cloning research. Those seem like the important ones.
If we move onto the improbable I'd say researching telepathy. I believe the greater mysteries of life would be ascertainable if you could get first-hand views of the world from hundreds of viewpoints. I hear (from House) that there is minor telepathic-esque devices in development, but I'd go all out for this. Seeing every possible angle on the world, basically living hundreds of lives, living on hundreds of worlds just as alien as the last but still technically the same earth as your own, seeing every possibility and every thought process. You'd see every angle, every possible thought on a situation, everything that it is to be human. The moral questions come in for privacy and control reasons.
And the shits and giggles response is giving different fuzzy forest critter breast implants.