I have to do this with sandbox games. I'm totally burnt out on ones that are set in a major city: GTA, Saint's Row, Mafia, The Saboteur, etc. I'm so sick of driving in games that I just don't want to play games where it's a major component anymore. I got pissed off at LA Noire when it punished me for making my partners do 90% of the driving (I'm referring to the "find the landmark" mission. If you haven't found them before you start that part, then it's excruciatingly tedious). Oddly enough, some sandbox games are immune: Bully, Red Dead Redemption, the last two Assassin's Creed games (which I guess are really a hybrid Action-Adventure-Platforming-Sandbox games). But that's because those games have so much great gameplay outside of travel.
I used to just have to put a lot of time between big city sandbox games. But then I hadn't played one for a year and tried to play Mafia II and didn't get very far. It wasn't a bad game. I just think I don't like those kind of experiences anymore at all.