Sort of how I feel: combat is decent, if at times lacking or constrained, and the levels feel good, while the story is a lot to be desired, and this feels a lot like a masturbatory product from NT. I can't help but think though that, since this is actually the first game NT has fully written, if they sort of felt like they could be all smarmy with the mop joke and kind of douchy behavior in the credits (yes, you're so badass for giving the finger while riding on a skateboard, I bet you were the coolest kid in school *yawn*)
I think the boss fights were overall fine. However both final bosses felt rather lacking (the actual final boss was too easy and had a contrived way of winning), and I think the Lilith boss fight is a good example of why a lack of lock-on doesn't work.
It occurred to me the other day though when thinking about the game's story that, all things considered, the villains are actually very non-threatening. Think about it, we never actually see the effects of virility on humans, Raptor news doesn't actually seem to be brainwashing the people if no one on the street recognizes Dante, and we never actually see what Mundus does that makes his "control the world through debt" plan all that effective or scary.