sounds kinda like what you'd get if you put your standard zombie movie, mixed with "The Running Man", mixed with the concept of "Fangus Clot" which doesn't sound too bad, now that I think about it.
But the concept is only so much of a game. What will this game be? The usual shooter, like we'd expect, or a Mass Effect kinda thing, where we get to decide gender and the like. And what of the atmosphere, scary, campy (like Dead Rising") or actiony. Not to mention, the only thing that separates games like Bioshock and Damnation is that one is handled well while the other isn't. None the less it sounds pretty good. If you do this right, it could end up being the next dead rising, a zombie game that's very clever about the zombie concept.
Can I add something to it. Like in RE4, the main character/dead rising, whoever he or she is, gets infected. Now in those games, infection doesn't really have any consequences in-game. Might I suggest that you do something like Eternal Darkness' sanity meter, in that the main character starts hullicinating, due to further infection from the zombie virus. Like, if you get bitten, your "sanity meter" goes down and you start hullucinating