Right now, I'm big into Netrunner, and my runner deck is as follows:
Basically, hit the corp's servers as hard as possible, and never let him score an agenda, prevent him from amassing too much money. It works pretty well, I feel.
Runner - Kate "Mac" McCaffrey
Diesel x3
Infiltration x3
Modded x2
Sure Gamble x3
The Maker's Eye x3
Tinkering x3
Special Order x2
Akamatsu Mem Chip x2
The Personal Touch x2
The Toolbox x1
Cyberfeeder x3
Battering Ram x2
Gordian Blade x3
Magnum Opus x2
Corroder x2
Ninja x2
Armitage Codebusting x3
Sacrificial Construct x2
Access to Globalsec x3

Diesel x3

Infiltration x3

Modded x2

Sure Gamble x3

The Maker's Eye x3

Tinkering x3

Special Order x2

Akamatsu Mem Chip x2

The Personal Touch x2

The Toolbox x1

Cyberfeeder x3

Battering Ram x2

Gordian Blade x3

Magnum Opus x2

Corroder x2

Ninja x2

Armitage Codebusting x3

Sacrificial Construct x2

Access to Globalsec x3

Basically, hit the corp's servers as hard as possible, and never let him score an agenda, prevent him from amassing too much money. It works pretty well, I feel.