Depends whether you want to pay for it or not.
If you're willing to splash the cash, Eset NOD32 is the best consumer antivirus program on the market, high detection rate on both heuristic and database scanning (scanning based on known viruses or based on behaviour for viruses not yet in the update list), low false positive rate, low system performance impact, the works. (It's the only one that got the full three star rating in AV Comparitives' reviews for all three sections)
If you're not willing to pay, Avira Antivir is the best free offering. Extremely high detection rate for known threats and good heuristic detection of new threats, but at the cost of quite a high false positive rate, and middling system performance impact.
Also: Do not use more than one antivirus program at the same time. As they will both be attempting to scan everything at the same time, you will multiply the impact they have on your system performance, and at worst their heuristic engines will pick each other up as suspect behaviour. Choose one and stick with it, run it alongside an on-demand only spyware scanner like Malwarebytes Anti-Malware.
Some spyware programs are super-paranoid about tracking cookies as well, which seem to inflate their number of detections.
Also, Spyware Terminator will throw up false positives, so watch out for what it's doing.
If you're willing to splash the cash, Eset NOD32 is the best consumer antivirus program on the market, high detection rate on both heuristic and database scanning (scanning based on known viruses or based on behaviour for viruses not yet in the update list), low false positive rate, low system performance impact, the works. (It's the only one that got the full three star rating in AV Comparitives' reviews for all three sections)
If you're not willing to pay, Avira Antivir is the best free offering. Extremely high detection rate for known threats and good heuristic detection of new threats, but at the cost of quite a high false positive rate, and middling system performance impact.
Also: Do not use more than one antivirus program at the same time. As they will both be attempting to scan everything at the same time, you will multiply the impact they have on your system performance, and at worst their heuristic engines will pick each other up as suspect behaviour. Choose one and stick with it, run it alongside an on-demand only spyware scanner like Malwarebytes Anti-Malware.
Depends how they list things, and what they look for. Antivirus programs won't remove BHOs and other annoying nonsense (MyWebSearch, etc), and they usually list one infection as one item, whereas spyware removers tend to list one file/registry key as one item. For instance, MyWebSearch is detected in Malwarebytes as around 200 "infections", whereas it's actually all one thing.AVG and Spyware Doctor spotted 10 things on my computer. Spyware Terminator found 1,439.
Some spyware programs are super-paranoid about tracking cookies as well, which seem to inflate their number of detections.
Also, Spyware Terminator will throw up false positives, so watch out for what it's doing.