Comedian wise? No. I don't particularly find most female comedians funny , even though I am a woman. Because it does start to sound like all of the same jokes after awhile - though I do have a few that I've found amusing. I'm not saying they aren't good people, or that they aren't funny when you talk to them personally, one-on-one; but when they get on stage it's just different.
The only real ladies-of-comedy I've ever laughed at were, French and Saunders (hilarious), Wanda Sykes, and Ellen Degeneres. Ellen is actually a favorite of mine, because, she deals with a lot of observational comedy. I like that.
Some female comedians usually try too hard. They try too hard to be rough and "I-don't-care". Swaggering , barking jokes, and taking stabs at shock comedy for a few laughs. I usually expect them to try to adjust their junk on stage. Then there are those female comedians who try far too hard to just appeal to the ladies in the audience. Talking about shopping, hating men, and whatever else they think will get the most laughs from their own gender. It's very hard for them to find middle ground in the first place; like any comedian. It's not an easy gig to try to appeal to everyone at one time, man or woman.
I've found more real my-side-hurts laughs with female friends (which I have very few of now), then female comedians. But that's just me. =)
Comedy is just like music, television shows, and what games you like. You just like them. You can't truly explain it to someone who doesn't understand, or doesn't like what you like. They'll never get it. No matter how many big words you use, or how many ways you try to get the reason into their heads. You just do. ^_^
(However, favorite male comedians = George Carlin, Billy Connolly,Patton Oswalt, and Louis C.K . They've had me in tears. Especially Connolly. That man is a legendary storyteller. =D)