Yup. I recently picked Resonance of Fate back up. I stopped playing it when I overhauled my living room and didn't have my PS3 hooked up for a few weeks... then I forgot about it for a year or so... Still haven't finished it, but I take it in smallish doses.
There are also games that I finish, then go back for another playthrough making different choices. I've put down Fallout: New Vegas five times now. Most recently, I finally bothered to grab the DLC, so I'm going through that slowly with my old characters.