Nothing will ever beat Deadpool in Marvel Ultimate Alliance.
Deadpool: [Leveling up] And now I'm better at doing whatever it is Wolverine does!
Deadpool: [Badly hurt] I need help! And a pony!
Deadpool: [after speaking with Nick Fury] Sir! Yes Sir! Stowing all stupid thoughts! Uh, is that vein on your forehead meant to be throbbing like that?
Deadpool: A haiku, by Deadpool: I hate broccoli / And think it totally sucks / Why is it not meat?
Deadpool: I'm low on energy, but full of vitamin C!
Tony Stark's Receptionist: Warning: a small thermonuclear device is missing, and Deadpool was last seen in the weapons lab.
Deadpool: Weasel old buddy! Where have you been hiding out?
Weasel: In the hospital, you stabbed me in the leg remember?
Deadpool: Oh yeah, but I had to, you were trying to steal my last Cheesy Puff
Weasel: It was my bag of Cheesy Puffs!
Deadpool: That's not how I remember it.
Deadpool: Oh, don't be such a stick in the mud. Come on, repeat after me: 'Spatula.'
Arcade: HELLO, Deadpool. Ready for a fun filled day in Murderworld?
Deadpool: Yup. I've got my sunscreen on and I've taken my motion sickness pills so bring on the rides!
Arcade: Oh, I don't think you understand. You're going to die here.
Deadpool: I know! Carnivals always slay me.
Arcade: No. You are going to physically die... as in stop breathing. You will cease to exist.
Deadpool: Riiiiiight... So do you have bumper cars here?
Arcade: Arrrgh!