Mass Effect, hands down.
Council : "There's a saying : even a broken clock is right two times a day. (or something)
Shepard : "Here's another saying : go to hell!"
Mira: It looks like you are trying to restore this facility. Would you like some help?
Shepard: Oh crap, a pop-up.
Urdnott Wrex: So this is the famous turian general? How did your kind ever defeat us?
General Septimus: I may be drunk, krogan, but you're ugly. And tomorrow I'll be sober.
Ashley Williams: That puts a whole new spin on the phrase "drop on the floor and give me twenty".
Commander Shepard: You still sassin' me soldier? I think you need more physical training.
Ashley Williams: Tsk. Now, skipper, what will it take to prove I'm in prime condition?
Conrad Verner: What if you signed me on as another Spectre?
Commander Shepard: Conrad, I haven't been shot in the head nearly enough times to make that sound like a good idea.
Tali'Zorah nar Rayya: How can you fight your own people?
Urdnott Wrex: Anyone who fights us is either stupid or on Saren's payroll. Killing the latter is business. Killing the former is a favor to the universe.
