Cancer Vaccine Found?

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Goldeneye1989

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Mar 9, 2009
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Yeah sadly it's not being cynical to say it's not going to stop all cancer's as each one has it's own little fun design to it.

hopefully though these three begin to get better and more efficient over time, as now we know where we can start. we now know that whatever they have done works against three diffirent types so now it's time to play Biomedical Jigsaw
 

Bob the Average

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Sep 2, 2008
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a cancer vaccine would be wonderful but as we hardly know the causes of cancer i imagine it will be quite some time before any thing like that is commonplace.
 

TaborMallory

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May 4, 2008
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Agayek said:
How exactly does a vaccine work on cancer?

Vaccines are forms of dead bacteria to help increase your body's resistance to that bacteria.

Cancer is otherwise normal cells that do not die as they should, doubling themselves nigh-endlessly.
I was about to say this. Oh well.

Yahoo News doesn't know how to research.
 

ReZerO

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Mar 2, 2009
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this is promising as well
http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20090519/ribavirin_090519/20090519/
Antiviral drug becomes promising cancer-fighter

Updated Tue. May. 19 2009 10:02 PM ET

CTV.ca News Staff

A commonly used antiviral drug that's already used to fight hepatitis C and HIV could also be used to treat 30 per cent of cancer types, according to a new study conducted on patients in Canada.

Doctors in Montreal tested the antiviral drug ribavirin on 11 patients with acute myeloid leukemia (AML), who had undergone several other treatments that had previously failed.

Nine of the patients saw their conditions improve within a matter of months, with one achieving complete remission and two achieving partial remission, all with few side effects. The results are published online in the journal, Blood.

Frank Klamph was one of the patients who benefitted from the treatment. Last fall, he was weak and ill with AML. After taking part in the study to test the experimental treatment, he achieved complete remission and was even able to leave hospital and scuba dive in Florida.

"Within two short months, it was like a miracle," he told CTV News. "I feel like the cancer is gone."

The researchers, led by Dr. Katherine Borden, at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal, say that ribavirin works by suppressing activity of the eIF4E gene, which becomes overactive in 30 per cent of cancer types and overproduces a protein that helps turn cells cancerous.

"In several of the patients, we had remissions -- which is completely unheard of for these kinds of patients. And in another subgroup of patients, we had really dramatic drops in the number of leukemia cells they had, including patients where we could no longer or barely detect any leukemia in them anymore," Borden explained.

"To have patients who feel good and can go out and have a life, and not be in hospital sick all the time, which is often the normal course of leukemia, that was really exciting for us and that's why we're excited."

Dr. Brian Leber, one of the other IRIC investigators involved in the study, says what makes the results so exciting for him is that ribavirin is an already established drug.

"This has been obtained with a drug that has been available for probably a decade," he said. "So unlike a lot of extremely promising cancer therapies that are in earlier stages of development, this is a drug that we could use immediately.

Leber was also pleasantly surprised by how quickly the treatments seemed to have an effect on patients.

"This type of response rate in a wide variety of patients, who have pretty advanced leukemia, would be considered pretty remarkable for any drug," he said.

"Certainly, considering how well it was tolerated and the fact that it's a very convenient oral therapy that can be taken at home, when you put all this into the mix I think it is quite exciting results."

Dr. Borden says ribavirin is likely to show promise for other types of cancer associated with dysregulation of the eIF4E gene.

She says the next challenge is to combine the promising antiviral with chemotherapy, to improve its effectiveness.

She says they also need to work on ways to combat the development of resistance to the drug.

With a report from CTV medical specialist Avis Favaro and producer Elizabeth St. Philip
 

FinalFrog

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Jun 1, 2009
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MasterSqueak said:
Leorex said:
theres not going to be one cure for cancer.
Negative person.
No, actually he's actually got it right as far as the opinion of the cancer research community goes. Cancer is not caused by a single mutation, it can be caused by a mutation anywhere the regulatory regions which control cell life cycle. We can try and figure out which regions most often cause certain cancers and create "cures" which specifically target cells who show signs of mutations in these regions, but that's only one type of cancer we're targeting. There's hundreds if not hundreds of thousands of regions that when mutated could potentially cause cancer. We may find a "cure for cancer" but it will almost certainly be for only one or two types of cancers out of the many that could occur. If you're really lucky you might find a cure for all the cancerous cells which originate from a given type of cell, but I'll bet you it'd really bad for the normal cells of that type as well... ;D

Also to spread some biology joy into your day here's a new theory from some recent research regarding cancer which was presented to me at one of the biology seminars I have to go to as part of my summer research job at college. =D

So you know stem cells? Those cells which can turn into any other type of cells in your body. One possible explanation raised recently for why people who have apparently been cured of cancer suddenly have a resurgence when they stop chemotherapy is that there might be Cancer Stem Cells which are not cancerous themselves but have been programed through mutations to produce cancerous cells. The bad side of this is that even if a "cure" which kills all the cancerous cells in your body may not cure you permanently. The bright side is that it's another avenue to fight the good fight. Creating drugs to attack Cancer Stem Cells if they do exist would increase the chances of recovering cancer patients tremendously. ^_^
 

manaman

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TaborMallory said:
Agayek said:
How exactly does a vaccine work on cancer?

Vaccines are forms of dead bacteria to help increase your body's resistance to that bacteria.

Cancer is otherwise normal cells that do not die as they should, doubling themselves nigh-endlessly.
I was about to say this. Oh well.

Yahoo News doesn't know how to research.
Good thing you didn't actually say that. Cause then you would both be wrong.
Vaccines are weak, dead, or similar enough viruses that your body can form anti-bodies against the real deal when it comes knocking.

You take penicillin or other antibiotics to kill off bacteria.

All tumors are called neoplasm, with only malignant ones being call cancer. All neoplasm are the result of neoplasia, which does not always form into a neoplasm (leukemia and the like). I think you can all look up the terms to find out more if you want to.

Basically benign neoplasm are not at risk of spreading to other organs. Pre-malignant does not currently have the mass to spreed, but will sometime in the future. Malignant is capable of spreading in process known as Metastasis.

Viruses are plenty capable of causing neoplasia. Bacteria, not so much.
 

Shapsters

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Dec 16, 2008
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inu-kun said:
They found the cancer vaccine years ago, but only really rich people and goverment employees know about it.
I agree, there is too much money going into the reaserch and 'finding a cure'. Cancer was cured long ago!
 

Motti

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Jan 26, 2009
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Wait? A cure for Cancer?
*grabs shotgun*
Time to prepare for an 'I am Legend' style apocalypse!
 

monalith

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Nov 24, 2008
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vaccine implies a viral cause so if not a type of cancer caused by a virus it bullshit.
 

justnotcricket

Echappe, retire, sous sus PANIC!
Apr 24, 2008
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Shapsters said:
inu-kun said:
They found the cancer vaccine years ago, but only really rich people and goverment employees know about it.
I agree, there is too much money going into the reaserch and 'finding a cure'. Cancer was cured long ago!
Ugh - the drug companies get more money from going public with the 'cure' and charging people for it than they do for speculating about cures and begging research grants. And even when the patents ran out and the drugs became generic, the pharmaceutical companies would still be coining money from new statins (anti-cholesterol drugs) they develop. Although cancer chemotherapeutics make up a large share of the global pharmaceutical sales, they are FAR out numbered by the painkillers and the antacids and the statins. FAR.

As for the article, things like this are not exactly new, they just take a while to get from the academic journals to the popular media. ADEPT, CDEPT and GDEPT treatments, as well as photodynamic, photothermal and combination therapies are currently being developed and approved - the process for making ONE new drug and testing it involves, on average, four stages of clinical trials, 10 years of research and development and a TON of money - into the billions. This ensures, hopefully, that the drug is as safe and effective as humanly possible. The problem with this article is that it has been dumbed-down to the point where it hardly even makes sense *shakes finger at Yahoo* - the problem isn't that Yahoo posts bogus articles, it's that it thinks we're all so thick that we can't understand a detailed explanation of the issue at hand.

Sorry for the rant - in short, yes, it's possible to 'vaccinate' against cancer. No, it's not yet possible to reliably treat all types of cancer with one therpeutic agent. I wish it were, even if it would put me out of a job =P
 

TaborMallory

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May 4, 2008
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manaman said:
Vaccines are weak, dead, or similar enough viruses that your body can form anti-bodies against the real deal when it comes knocking.

You take penicillin or other antibiotics to kill off bacteria.

All tumors are called neoplasm, with only malignant ones being call cancer. All neoplasm are the result of neoplasia, which does not always form into a neoplasm (leukemia and the like). I think you can all look up the terms to find out more if you want to.

Basically benign neoplasm are not at risk of spreading to other organs. Pre-malignant does not currently have the mass to spreed, but will sometime in the future. Malignant is capable of spreading in process known as Metastasis.

Viruses are plenty capable of causing neoplasia. Bacteria, not so much.
Now, I'm not an expert on the subject. All I know is that a vaccine is used to kill or repel viruses. I also know that cancer is the abnormal growth of otherwise normal cells.

I don't really know what you were talking about, but I'll take your word for it. Right now, I'm too lazy to research.
 

ThrobbingEgo

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Nov 17, 2008
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letsnoobtehpwns said:
It's not real. They probably tested it on one person who had skin cancer.
You could have at least read the article before totally ignoring it. What they're trying to do is get the immune system to "see" the cancer, which is difficult because cancerous cells are just really messed up human cells. It's also not really a "cure" yet, more of a treatment.

It's called a vaccine because it gets your immune system to "see" the cancer.
http://en.wikipedia.org/wiki/Vaccine

And yes, you can have vaccines for diseases that aren't viral. Like cancer.
http://en.wikipedia.org/wiki/Cancer_vaccine