Cancer will always be with us, according to more recent research

Recommended Videos

DefunctTheory

Not So Defunct Now
Mar 30, 2010
6,438
0
0
Mr.Savage said:
In the original post, I linked to a news segment about DMSO, a substance whose clinical usefulness and safety has been very well documented both in and out of the laboratory, yet it remains out of reach to physicians for anything except the treatment of interstitial cystitis, a condition for which DMSO is the only effective modality.

The reasoning for this is openly admitted by both the regulatory agencies and Big Pharma; the former insists it would be a regulatory nightmare, the latter indicates that, being a completely natural substance and therefore unable to be patented, there's no money to be recovered from the approval process, as it is well known that DMSO is a byproduct of paper manufacturing, and therefore cheap to produce. This eliminates the justification of a high markup to recoup costs.

It remains unapproved for use in humans, despite an embarrassing amount of evidence and testimony that it is both safe and effective in the alleviation of many different ailments.

Given this and other such cases, I struggle with the idea that these entities are entirely benign.
I just wanted to point out that a quick google search seems to indicate that DMSO is used in typical cancer treatment. How, you ask? It binds and negates some chemotherapy drugs, so it's used to neutralize 'leaked' chemo. That's right - It doesn't kill tumors, it kills tumor killing drugs.

Learn something new everyday.
 

Thaluikhain

Elite Member
Legacy
Jan 16, 2010
19,538
4,128
118
Mr.Savage said:
The_Kodu said:
A lot of Big Phrama work is centred round re-fining drugs to produce them more efficiently and create more efficient drugs with less side effects.

Creating an anti-cancer drug would be a whole new area of work to refine it's production process and reduce side effects.
I appreciate this point of view, but answer me this: would Big Pharma embrace a superior cancer treatment that did not take the form of a pharmaceutical?
Like what?

Surely the same would apply as to cancer prevention methods like wearing sunscreen?
 

Mr.Savage

New member
Apr 18, 2013
107
0
0
AccursedTheory said:
I just wanted to point out that a quick google search seems to indicate that DMSO is used in typical cancer treatment. How, you ask? It binds and negates some chemotherapy drugs, so it's used to neutralize 'leaked' chemo. That's right - It doesn't kill tumors, it kills tumor killing drugs.

Learn something new everyday.
Good catch. I never meant to imply that DMSO was in any way effective against cancer. Due to its solvent properties and free radical scavenging action, it will neutralize Chemo.

It is just the thing for a sprained ankle, though. It kills pain and reduces swelling like an NSAID, but without any liver or renal toxicity. The fact that it isn't made available for such uses is criminal.

It simply breaks down into dimethylsulfide in vivo.


I love the stuff.
 

Sampler

He who is not known
May 5, 2008
650
0
0
Your argument is illogical. Your logical premise from what I can determine is:

If we make a cure for cancer, no one will have cancer so we can't make continued profit, ergo we keep them in protracted symptom management.

However, this misses a vital part, new cancer patients are diagnosed daily, so new customers are available daily. It's not like cancer is a contagion, that eradicating it like small pox means no one will ever get it again. You will still have hundreds of thousands to millions of customers per annum for your cure.

Your argument seems more like a straw-man attempt to breed fear of "big pharma".
 

P. K. Qu'est Que Ce

New member
Feb 25, 2016
81
0
0
renegade7 said:
P. K. Qu said:
renegade7 said:
Yopaz said:
renegade7 said:
May I ask what background you have? I am asking because your post was very well written and really gave a great introduction to what cancer is.
Thanks!

My background is not actually medical. I'm in graduate school working towards a PhD in high-energy and plasma physics. But my undergrad degrees were physics and biochemistry, so I had some exposure to cell biology. That also came with the requisite "science in society" courses, which is basically academic-speak for "Identifying pseudoscience". I'm also currently an organizer for my college's student skeptic society, so I actually have some involvement in pro-skeptic activism (mostly just chasing down students who sell phony "study drugs", but there is some bigger advocacy stuff).
This is totally off topic, but is there any chance that you'd be able to explain to a simple fellow like myself what a "Superthermal" effect would be in relation to a laser?
So the first law of thermodynamics is "Total energy = heat added + work done", or U = Q + W (sometimes U = Q - W, Q + W means W represents "work done on the system", Q - W means "work done by the system"). Heat energy refers to the kinetic energy of the atoms in the system (the energy that makes them move around, more heat means faster atoms), work refers to energy gained or lost by all other sources.

"Superthermal" means that a system has energy that is not due to heat energy. In regards to a laser, I assume that refers to energy stored in the laser medium that is not due to the kinetic energy of the atoms in the medium. So for instance, if you're using a gas laser and some of the atoms or molecules ionize (become charged), they're storing energy that didn't come from the heat energy of the particles in the gas. Since atoms and molecules only store energy in discrete quantities, the energy distribution among all of the particles in the medium is going to be made inhomogeneous. Since a laser works by raising the energy level of the atoms in its medium to an excited state so that they all discharge at the same time, this will make the pulses of the output longer, meaning a lower-quality laser that is harder to control at higher pulse frequencies. The picture (I apologize for my horribleness at using Paint) hopefully explains what this would cause more clearly, ideally you'd want all four of the atoms to reach the excited state at the same time.


Hope that helps :)
Thanks! I know enough about lasers and thermodynamics to understand what you're driving at, and in fictional context it suddenly makes a lot of sense. You were absolutely right, it was a gas laser, and that gas was being drawn from the corona of a star. Your explanation makes the term comprehensible for me finally, thank you.
 

Mr.Savage

New member
Apr 18, 2013
107
0
0
The_Kodu said:
They already do it's called Radio therapy.
Radio therapy does not negate the need for Chemotherapy. I was referring to a non-chemical modality which will obsolete Chemo and X-Ray.

Mr.Savage said:
What frustrates me is the forgone conclusion that yet another expensive drug is the only way; which suggests an obligated hostility toward anything that does not strictly rely on a chemical mechanism to achieve the desired result.
The_Kodu said:
Well simply put on one level or another everything is chemical mechanism to a degree.

I'm not sure what you're suggesting as the alternative here. Others have suggested faith healers and the like but well I've already said my piece on them but can expand it more if required.
I'm suggesting something like the therapies used by Rife or John Holt. Both show positive results with absolutely no side effects.

Faith healing is for the birds, in my opinion.



Mr.Savage said:
I know it is very easy to dismiss such a thought process as fancifully ignorant, but I'm not new to this field of study.

There is a consensus among the rational set that a more effective treatment of cancer must, of necessity, be expensive to discover and expensive to produce. After all, look at how many billions have been spent just to get us were we are today.

So when something is proposed which doesn't fit that model, it is unceremoniously denounced, and its originator chastised for suggesting it.
The_Kodu said:
Well yes because it's widely accepted faith healing and the like is mostly if not entirely scam work and most solutions are going to be from either principals of physics or Chemical mechanism to solve it.

The idea of the new form of Tiny germ isn't seemingly widely accepted as to the best of my knowledge (not being a biologist) it's not been replicated or proven by other scientists.
Mr.Savage said:
In the original post, I linked to a news segment about DMSO...
The_Kodu said:
From my limited experience lots of drugs need a lot of testing to see their effectiveness on certain conditions and their cost effectiveness.

Drugs are trailed for years because the potential harmful impact of them may not be immediately apparent.
DMSO was found safe and effective for everything from aches, pains, burns, cuts, scrapes, acne, arthritis, stroke, to spinal cord injury.

Mr.Savage said:
It remains unapproved for use in humans, despite an embarrassing amount of evidence and testimony that it is both safe and effective in the alleviation of many different ailments that aren't cancer.
The_Kodu said:
Part of that is actually due to the fact in interferes witch chemotherapy. The concern is that a lot of the claims for DMSO being useful against cancer is coming from DMSO distributors not independent tests from what I can tell.

DMSO *Is Not* useful in the treatment of cancer. DMSO *is* useful for the ailments listed above, and should be sold cheaply by all pharmacies for everyday use.

It would cost more to get DMSO approved for sale to the public than could be recovered. So it isn't done. Which is fine by me, as I buy mine from the Veterinarian.
 

Mr.Savage

New member
Apr 18, 2013
107
0
0
rcs619 said:
See, now you're claiming that there is some as of yet unknown microbe (which a lot of sites related to Rife can't seem to decide if it's a bacteria or a virus) that is some sort of universal cause of cancer. You've just lost me.
rcs619 said:
Also, I feel like I should point out that we can image bacteria under an electron microscope just fine. The fact that they die in the process doesn't actually matter.
Dead wrong. This was the entire reason Rife built his microscopes, he wished to observe micro organisms in their live state so that he could determine their resonant frequency for devitalization.

But hey, science is catching up to him so that's got to count for something: http://articles.economictimes.indiatimes.com/2011-03-02/news/28649307_1_microscope-viruses-cells


Concept: https://youtu.be/cPALfz-6pnQ?t=7s


Application: https://youtu.be/ZWqEmzCSSzU?t=39s




rcs619 said:
Do you see how unbelievable it is that thousands of scientists, from dozens of different countries, under the jurisdiction of both government and private interests would not have caught this "bacillus X" within the last 60 years?
My point exactly. The BX microbe has been observed under SEM, but it is regarded merely as an optical anomaly, not a microbe.

rcs619 said:
In his lab. Using his microscopes. Singular results mean next to nothing in science. Show me peer-reviewed articles of other scientists not affiliated with Rife (or better yet, skeptical of Rife) that have independently verified his claims.
https://youtu.be/sBx2JYMCuck?t=6m54s


Why has there been no attempt at independent verification of the process depicted in the above video link? I mean, it's practically a tutorial.


rcs619 said:
It does, however, fit every classical definition of a conspiracy theory (reducing a complex issue down to a simple solution, and then having that solution be hidden through the actions of a gigantic cabal for decades), and that it sounds fairly ridiculous when put under the tiniest degree of scrutiny.

I will concede, this video makes a damned compelling argument in favor of what you're saying:

 

Mr.Savage

New member
Apr 18, 2013
107
0
0
The_Kodu said:
The statements I can find on DMSO seem to suggest concerns of it's potential as an irritant and more specifically the potential for unwanted substances to be more easily absorbed by the skin by it's use (AKA that harmful stuff in cleaning products and things that our skin normally blocks).
These things are both true. Interestingly, DMSO is not as effective when used full strength, so it is typically prepared as a 70% or 50% solution with distilled water.

I mix mine with organic Aloe Vera juice, and this greatly mitigates any chance of irritation.

Due to it's solvent properties, the skin must be absolutely free of any contaminants or they will be dragged into the bloodstream. Conversely, any beneficial substance of low molecular weight will also be delivered to the bloodstream.

I use this characteristic of DMSO to enhance absorption of Vitamin B12 using the methylcobalamin form. It works a treat.


The_Kodu said:
It's also suggested it could have a possible nerotoxic effect over high level or low level long term exposure.
I've looked for years for data that supports this, and I can't turn any up. Incidentally, the man who first championed the use of DMSO, Dr. Stanley Jacob, MD, stated many times that starting in 1964 when he first started experimenting with DMSO, he would place a half-teaspoon of the stuff in Orange Juice and knock it back faithfully every morning. He said he did this because "if it's going to hurt anybody, it may as well be me, hell, I'm the one promoting it."

He passed away at age 91 in January of last year. He never reported any change while ingesting DMSO.
 

FalloutJack

Bah weep grah nah neep ninny bom
Nov 20, 2008
15,489
0
0
I have a fairly-important question about cancer, and I think this thread begs its asking if it hasn't been asked already:

Cancer is essentially a case of a group of cells who alter their structure and their function to essentially grow in a prolific manner that works against the body which it has been born into. Has anyone ever found out what exactly cancer is actively creating? All these tumors and tendrils grow and regenerate like hell, resist multiple means of destruction, and sometimes resurge in again later in life after a period of dormancy. It's some very adaptive shit, if as Dr. Malcolm says "Life will find a way", what's this particular living cell achieving? It's not like viruses or bacteria, it's not parasitic or symbiotic, and it does not pass along to anyone EXCEPT in whatever gene activates a cancer cell in the first place. So, where does it come from and where is it going?
 

rcs619

New member
Mar 26, 2011
627
0
0
FalloutJack said:
I have a fairly-important question about cancer, and I think this thread begs its asking if it hasn't been asked already:

Cancer is essentially a case of a group of cells who alter their structure and their function to essentially grow in a prolific manner that works against the body which it has been born into. Has anyone ever found out what exactly cancer is actively creating? All these tumors and tendrils grow and regenerate like hell, resist multiple means of destruction, and sometimes resurge in again later in life after a period of dormancy. It's some very adaptive shit, if as Dr. Malcolm says "Life will find a way", what's this particular living cell achieving? It's not like viruses or bacteria, it's not parasitic or symbiotic, and it does not pass along to anyone EXCEPT in whatever gene activates a cancer cell in the first place. So, where does it come from and where is it going?
It's not achieving anything at all, besides its own proliferation. It's basically a bunch of cells gone rogue that reproduce and spread out of control, completely indifferent to whether or not that proliferation is harmful to their host body. They just keep making copies of themselves (and their damaged genes), and spread along destroying other healthy tissues as they go (to the point of eating away at bones and organs in some cases) until they're destroyed, removed or the host dies. There's no broader function or organization to cancer, it just creates these chaotic bundles of defective cells that do nothing besides suck up resources, damage surrounding cells or prevent them from doing their jobs properly, and make more copies of themselves. Eventually they make enough copies, and have such a destructive effect, that organs start to fail.

Your body is normally very good at preventing cancer. There's multiple steps within the cell division cycle that are purely there to check for replication errors and either repair them or destroy the defective cell outright before it gets the chance to do anything. Other cancerous cells are destroyed by your body's immune system if they slip past the genetic-level safeguards. The issue is when a cell becomes cancerous, but its cell-surface markers remain intact. Those markers are how your body determines what lives and what dies. Cells infected by viruses, for example, will actually display a suicide message on their surface markers to attract certain white blood cells to kill them before the virus is done reproducing inside of them. When a cancer cell has otherwise normal markers though, it's just a normal cell as far as your body is concerned, so it gets left alone.
 

Thaluikhain

Elite Member
Legacy
Jan 16, 2010
19,538
4,128
118
FalloutJack said:
I have a fairly-important question about cancer, and I think this thread begs its asking if it hasn't been asked already:

Cancer is essentially a case of a group of cells who alter their structure and their function to essentially grow in a prolific manner that works against the body which it has been born into. Has anyone ever found out what exactly cancer is actively creating? All these tumors and tendrils grow and regenerate like hell, resist multiple means of destruction, and sometimes resurge in again later in life after a period of dormancy. It's some very adaptive shit, if as Dr. Malcolm says "Life will find a way", what's this particular living cell achieving? It's not like viruses or bacteria, it's not parasitic or symbiotic, and it does not pass along to anyone EXCEPT in whatever gene activates a cancer cell in the first place. So, where does it come from and where is it going?
To add to what rcs19 said, asking what it is creating and where it is going is attributing purpose where there is none. There isn't even the usual implied purpose of keeping the organism together.

If we were to anthropomorphise it, it's a mistake, nothing more.
 

P. K. Qu'est Que Ce

New member
Feb 25, 2016
81
0
0
I just want to point out to anyone reading this thread, that by no means should you ever just compound and use your own DMSO, or use DMSO off-label in general. I doubt that anyone would here would be swayed by an obviously disturbed view on medicine and magic, but I feel like it has to be said anyway.

DMSO can be dangerous, and you probably don't know if you're allergic to it either. Most of all though, in no way does it perform as some miracle substance, any more than colloidal silver is the miracle antibiotic/antiviral. Please think for yourselves, and consider that someone might hold passionate beliefs rooted in delusions.
 

P. K. Qu'est Que Ce

New member
Feb 25, 2016
81
0
0
FalloutJack said:
I have a fairly-important question about cancer, and I think this thread begs its asking if it hasn't been asked already:

Cancer is essentially a case of a group of cells who alter their structure and their function to essentially grow in a prolific manner that works against the body which it has been born into. Has anyone ever found out what exactly cancer is actively creating? All these tumors and tendrils grow and regenerate like hell, resist multiple means of destruction, and sometimes resurge in again later in life after a period of dormancy. It's some very adaptive shit, if as Dr. Malcolm says "Life will find a way", what's this particular living cell achieving? It's not like viruses or bacteria, it's not parasitic or symbiotic, and it does not pass along to anyone EXCEPT in whatever gene activates a cancer cell in the first place. So, where does it come from and where is it going?
There is no plan, but there is a reason that tumors grow in certain ways, and it's not purely random. Each living cell, tumor or otherwise, needs a steady supply of nutrients, oxygen, and a means to get rid of metabolic waste. In practice, this means access to the blood supply. What most tumors end up doing is following basic cellular programming to a destructive degree. Most cells in our bodies are programmed to react in certain ways to their chemical and physical environment. It severely limits what they do, and sort of connects them to the larger network of other cells and the body at large.

Cancer cells have gone haywire, specifically in their reproductive aspects (there is more to it, but this is the essential point) and are reproducing without a homeostatic relationship to surrounding tissues. They are in essence, in it for themselves, and no longer part of a cooperating organism. The body generally makes some attempt to kill it, strangling small blood vessels and sending immune cells to attack the cancer. The cancer responds (not intelligently) by trying to get more blood, more food, and it does this by growing and reproducing. A tumor is just a big, messy mass of tissue that was all trying to get food and oxygen.

As the tumor grows though, since there is no plan and each cell is just trying to stay alive, the tissues they form are weak and unable to sustain themselves. Large tumors become necrotic (they die) because they're just masses of tiny blood vessels, and not made to spread oxygen and food throughout the bulk of the tissue. Cancers in the bone lead to porous, deformed bone because the cancer isn't trying to be a dense bone, or packed along the existing extracellular matrix, it's just growing outwards looking for food.

In essence, cancer is the birth of a rogue cell line in your own body, and it takes you over, killing you in the process. It out-competes your original cells for food and space, and since you need that to live, you die. In the process it replaces parts of you that are critical to your survival, like your lungs, or brain, or bones, or the elements of your blood. It's the body gone haywire, resorting to a kind of "original" biological plan, that's all.
 

BarkBarker

New member
May 30, 2013
466
0
0
I'd hate for it to ever be gone, its a big threat to our lives and we need threats or we'll all just die to the next super virus we helped forged in the eternal arms race between creatures and defects/viruses/infections/diseases/etc.
 

FalloutJack

Bah weep grah nah neep ninny bom
Nov 20, 2008
15,489
0
0
rcs619 said:
thaluikhain said:
P. K. Qu said:
It was important for me to ask because of its confusing nature, in that cancer cells do more and do differently than other hindering organisms, and that this study says what it says. (Your information about it has been very interesting.) I do not anthropormorphise it, but rather wonder about the bizarre programming that leads to the creation of the cell masses. Like the cells in our body normally, it has a series of tasks engrained into its very core that it follows. It is basically a malfunction, but the malfunction is uniform. A cancer cell operates to survive and reproduce, thus it makes more of the same. I feel as though what should normally happen is that all of them from the first cell should not behave as a colony, but as similarly self-supporting malfunctioning cells even unto each other. And if not, can they be made to canniballize each other?
 

P. K. Qu'est Que Ce

New member
Feb 25, 2016
81
0
0
FalloutJack said:
rcs619 said:
thaluikhain said:
P. K. Qu said:
It was important for me to ask because of its confusing nature, in that cancer cells do more and do differently than other hindering organisms, and that this study says what it says. (Your information about it has been very interesting.) I do not anthropormorphise it, but rather wonder about the bizarre programming that leads to the creation of the cell masses. Like the cells in our body normally, it has a series of tasks engrained into its very core that it follows. It is basically a malfunction, but the malfunction is uniform. A cancer cell operates to survive and reproduce, thus it makes more of the same. I feel as though what should normally happen is that all of them from the first cell should not behave as a colony, but as similarly self-supporting malfunctioning cells even unto each other. And if not, can they be made to canniballize each other?
It's not so much a new and bizarre program, as it is taking the limiters off of the existing program. For those of our cells with a complete nucleus, they have our who genetic plan to work with, remember? It's less like inserting a new program, and more like a chicken with its head cut off. You can't really do something new and interesting with it, you can't train it. It just runs around randomly, driven by its most basic programming (brain stem) until it runs out of limited energy and dies. Cancer, the disease, is similar.

OT: OP needs to read this, stat: http://quillette.com/2016/02/15/the-unbearable-asymmetry-of-bullshit/
 

FalloutJack

Bah weep grah nah neep ninny bom
Nov 20, 2008
15,489
0
0
P. K. Qu said:
FalloutJack said:
rcs619 said:
thaluikhain said:
P. K. Qu said:
It was important for me to ask because of its confusing nature, in that cancer cells do more and do differently than other hindering organisms, and that this study says what it says. (Your information about it has been very interesting.) I do not anthropormorphise it, but rather wonder about the bizarre programming that leads to the creation of the cell masses. Like the cells in our body normally, it has a series of tasks engrained into its very core that it follows. It is basically a malfunction, but the malfunction is uniform. A cancer cell operates to survive and reproduce, thus it makes more of the same. I feel as though what should normally happen is that all of them from the first cell should not behave as a colony, but as similarly self-supporting malfunctioning cells even unto each other. And if not, can they be made to canniballize each other?
It's not so much a new and bizarre program, as it is taking the limiters off of the existing program. For those of our cells with a complete nucleus, they have our who genetic plan to work with, remember? It's less like inserting a new program, and more like a chicken with its head cut off. You can't really do something new and interesting with it, you can't train it. It just runs around randomly, driven by its most basic programming (brain stem) until it runs out of limited energy and dies. Cancer, the disease, is similar.

OT: OP needs to read this, stat: http://quillette.com/2016/02/15/the-unbearable-asymmetry-of-bullshit/
Ah, so then it's a zombie!

*Pause*

Uh oh...
 

P. K. Qu'est Que Ce

New member
Feb 25, 2016
81
0
0
FalloutJack said:
P. K. Qu said:
FalloutJack said:
rcs619 said:
thaluikhain said:
P. K. Qu said:
It was important for me to ask because of its confusing nature, in that cancer cells do more and do differently than other hindering organisms, and that this study says what it says. (Your information about it has been very interesting.) I do not anthropormorphise it, but rather wonder about the bizarre programming that leads to the creation of the cell masses. Like the cells in our body normally, it has a series of tasks engrained into its very core that it follows. It is basically a malfunction, but the malfunction is uniform. A cancer cell operates to survive and reproduce, thus it makes more of the same. I feel as though what should normally happen is that all of them from the first cell should not behave as a colony, but as similarly self-supporting malfunctioning cells even unto each other. And if not, can they be made to canniballize each other?
It's not so much a new and bizarre program, as it is taking the limiters off of the existing program. For those of our cells with a complete nucleus, they have our who genetic plan to work with, remember? It's less like inserting a new program, and more like a chicken with its head cut off. You can't really do something new and interesting with it, you can't train it. It just runs around randomly, driven by its most basic programming (brain stem) until it runs out of limited energy and dies. Cancer, the disease, is similar.

OT: OP needs to read this, stat: http://quillette.com/2016/02/15/the-unbearable-asymmetry-of-bullshit/
Ah, so then it's a zombie!

*Pause*

Uh oh...
YES!!! If you think about it, isn't a zombie just disease, personified? Mindless, relentless, even to the point of utter self destruction, the zombie/disease exists only to feed and by feeding, make more like it. That's a fatal disease in a nutshell, and that's cancer.