Change one letter in a game's title and you get....

[TPiddy]

Deus Ed - a day in the life of a guy named Ed.
Borderhands - you play a mime trapped in an invisible box
God of Tar - you play as an oil tycoon
Red Head Redemption - One man finally snaps on kick a ginger day
Dead Spice - You have to solve the mystery of the slaughter of paprika crops worldwide
Bears of War - who needs chainsaw lancers when you have bears?
LittleBugPlanet - Hmm, this could actually be fun! Like Sim Ant...
Wii Shorts Resort - About a gay caribbean holiday spot
Left 4 Deaf - a game where your team mates can't hear you

Planks vs. Zombies - Try to stop the invasion using slabs of wood

 

[Akalistos]

Lass Effect? (it's what happens when a woman walks past a pub in yorkshire XD )

Yeah, Major Wayne goes around town doing the "shwing" move each time he see a Lass.

[small](kudos to who get the reference)[/small]

 

[Akalistos]

Pants vs. Zombies.
I'd probably buy that game.

But doesn't that mean we get naked Zombies with rotten flesh? No thank you, I'll pass that one.

 

[Miffmoff]

Command and Conquer: Bed Alert, communist ants try to take over a capitalist bed

 

[Mr_Universal]

(just adding one though..) supper Mario, from the makers of other food games such as Bass Effect and the award winning Left for Bread

 

[Squilookle]

***Coming soon to a game store near you!***

Raise you very own herd of cows... on the ocean... in 'Cattlestations: Pacific'
Then take on endless waves of enemies in 'Tide Fighter'

It's the alpine carnage you've always wanted in 'Crimson Skiis'
And the return of the beloved stealth party series with 'Silent Munter 5'


Oh, and it's a contest to get the best angle on your plumber's crack in 'Super Ma Rip Sunshine'

Fable becomes Gable.
Everyone's favorite game about the triangular top part of people's houses! Morality choices ensue!

I laughed so hard at that one! Brilliant!

Actually they're all getting better in general this page.

 

[ConfusedCrib]

Prey becomes Pray, Kinect exclusive

 

[Snarky Username]

Ocarina of Time becomes Ocarina of Lime. The most refreshing musical instrument ever!

 

[Zenn3k]

Final Pantasy

The epic quest to find woman's panties.

 

[Enigmers]

God of Bar
Follow the adventures of Kratos as he tries to satisfy every alcoholic on Mount Olympus!

 

[PaintDrinker]

GTA san andreas ---> GTA Say andreas: the epic story of a man with a speech impedimimimimimint

Need for speed ---> weed for speed: the most realistic simulated drug dealing experience in the known world.

Fallout 3 ---> Falloot 3: a scotsmans stuggle for survival in a land where there are no sausage rolls.

 

[Blue Musician]

RAGE-RAPE
Silent Hill-Silent Hell
Braid-Brain
Morrowind-Borrowind
World of Goo-World of Boo

Well, I'm run out of ideas, but here are some if you add some letters:
Resident Evil 4-President Evil 4
Quake 4-Wuaker 4

ETC,ETC,ETC.

 

[Blue Musician]

GTA san andreas ---> GTA Say andreas: the epic story of a man with a speech impedimimimimimint.

LOL I liked that one,and also WELCOME TO THE ESCAPIST!

 

[Lambi]

Silent Pill. It's the pill that'll make your voice...disappear!

 

[PaintDrinker]

thanks Khaiseri.

 

[Fallen-Angel Risen-Demon]

Lara Croft: Womb Raider

Gaming's most famous archaeologist works nights as an abortionist.

Although there is a porn movie called Womb Raider, believe it or not. So someone beat you to that.

*sigh* rule 34 or is it 31 I forget but anywho
Mean fortress 2. The Fortress is back and this time... MEANER!

 

[SomethingUnrelated]

Lara Croft: Womb Raider

Gaming's most famous archaeologist works nights as an abortionist.

XD Ahhh, that had me laughing sooo much...

 

[Xazetuf]

Par Cry

Stop the evil Wiley from threatening the land of Stoke using the power of Dun Know to Slew Dem.

 

[AvsJoe]

Pants vs. Zombies.
I'd probably buy that game.

I wouldn't touch that game with a 10ft WiiMote. The title implies that the zombies aren't wearing pants. Zombie wangs? *shudders*

 

[Marmalade]

Fed Dead: Redemption. You eat til you die and then your brother kills the chef.