Change one letter in a game's title and you get....

[Egitor]

Left nor Dead: After finally being rescued permanently from the zombie-infested streets, you try to rebuild your life in a small village as it fills up with other survivors brought in by the rescue chopper.

Oblivious: Playing as a shopkeeper in this Bethesda RPG you have to keep your wife out of the loop on all the evil running around just outside the door.

Jock Band: When the quarterback of this American football team breaks his leg he instead teams up with other injured jocks to make it in music instead.

Blut: In this high-speed racer game you use various power-ups and the power of your front bumper to smear your opponents blood across your windscreen.

 

[WhiteFangofWhoa]

Metroid Crime- Renounced by the Federation for destroying BSL, Samus is forced into taking jobs from the underworld.

Moral Kombat - The battle to the death between outraged 'moral guardians'. No fatalities, they simply lecture their conquered foe to death or conversion. Joe Lieberman as a hidden character.

Super Paler Mario
Failout 3
Wild Arts

 

[Diligent]

Demon's Soups
I can't even think of what that would be about, but it sounds funny.
I'm just picturing a monster with a chefs hat saying,
"This weeks demon soup is grilled baby and entrails, seasoned with virgin tears and topped with an angel wing garnish."

 

[Billion Backs]

Cod of War - The most brutal fishing simulator ever.

Edit: I refuse to believe I'm the first one to come up with it, and I'm too lazy to read through 5 more pages... So if I'm accidentally stealing someone's line, sorry.

 

[Nautical Honors Society]

Batman Arkham Asylum becomes...Fatman Arkham Asylum, a game about crazy people that are also morbidly obese.

 

[Pinstar]

Sim City= Sin City, where you try to get the crime rate as high as possible
The Sims= The Dims, A more accurate description of their intelligence level
Civilization V= Civilization X, Sweet, I went into the future and got an advanced version of the game, buah hah hah.

 

[Yopaz]

D.E.A.R.
Mario Fart.
Perfect Bark.
Donkey Kong Jungle Meat.
Resident Evil Hero.
Alone In The Park.
Wii Aports.
Guild Sars.
Tears of War.
Removing one letter and we get Ass Effect.

 

[FURY_007]

Twister Metal, You play a tornado going through towns, listening to heavy metal music

Barkwatch (Darkwatch, PS2 game), You, well, you watch bark lol.

Sid Meier's Pilates! (sp?) very well done pilates sim.


I love this thread!

 

[DRTJR]

Tetroid where Samus faces the evil of the TETRIS BLOCKS

Legend of Zelda: Spirit Racks, It's Link and Zelda Cooking Moblins


Tar For

Guitar Zero

Alan Bake a tale of a chef fighting against Zombie cakes

 

[Deleted]

Portal -> pornal : you use the power of portals to have sex with yourself.

 

[Limzz]

President Evil. Battle dead and living U.S. presidents in a dungeon.

 

[zehydra]

Majora's Mast: Majora's mask windwaker mash-up

Sport/Store/Spare/Shore/Score (Spore)

 

[Truehare]

Max Rayne (Bloodpayne?), where you play a tortured female vampire who likes to monologue a lot.

Callout 3, where everyone you meet just won't shut the fuck up.

Serious Dam, you have to defend a river barrier against countless alien attacks (argh!).

Boom 3, when Earth decides to stop sending space marines to fight the demons and just blow the shit out of Mars and its moons.

Ok, after that last one, I know it's time to stop...

 

[Housebroken Lunatic]

Majora's Mast: Majora's mask windwaker mash-up

... Im truly sorry for this, but the title "Majoras Mast" sounds like a cheesy pornoflick to me. Three guesses what the word "Mast" in the title would be a euphemism for.

 

[GothMatt]

Bioshock -> BioShack

A game where you have to create your own structures using nothing more than fungi and moss. It's a lot like Sims.

 

[open trap]

Call of Duty becomes Mall of Duty, where you can get a shovel full of shit half price each weekend!

 

[Haagrum]

Mash Effect
A gripping sci-fi epic set in a universe where scientists have unlocked the power of mashed potatoes to control the fabric of space and time itself.

Bears of War
Fight to save humanity from the Locust swarms as a tooled-up and armed-to-the-back-legs grizzly bear.

Dawn of Bar 2
The Space Marines put their genetically-enhanced bodies to a mission of real importance - drinking the bars dry on every planet in the Imperium.

 

[Hothcliff]

Banjo-Pooie
The Bobbit
Hallo
Star Box 64
Starbucks Adventures
Super Bario Bros
Super Wario Sunshine
Pokemon Bed
Pokemon Mellow
Pokemon Sliver
Pokemoan
Donkey Bong Country
Little Pig Planet
Ball of Duty 2
Call of Booty 4
Super Slash Bros
Super Smash Bras Melee
Mortal
Portage
Half Lie 2: Episode 3
Team Furtess 2
Prince of Pursia
GED of War
Bears of War 2
God of Bar 3
Maze
B.E.A.R.
T.A.L.K.E.R.: Clear Skype
Metro ID
Wii Spots
Mass Affect
Nights of the Old Republic

...wow that's a lot.

EDIT: Ninja'd and a half

 

[Dapper Ninja]

No More Heroes becomes No More Herpes.