"There are more things in heaven and Earth, Horatio, than are dreamt of in this man's mortal fancy..." - William Shakespere, "Hamlet".
Is there a soul? Absolutely. Nobody, even the "it's just chemicals" supporters, dispute that. You must assume that it exists to speculate on how it works. The question is, as I've postulated, "How does it work?". Is it mystical energy? a form of magic? a divine miracle? or a product of chemicals? Science cannot answer where it comes from, what is its purpose, why does it work, what happens to it when you die, etc.. Religion and mysticism cannot (or rather, do not) examine the mechanics of what exactly it is, what it does, how to define it, etc.. The answer lies somewhere in between.
Scientists, philosophers, and all sorts of scholars have been struggling with this very question for centuries and odds are we'll never reach a satisfactory conclusion from any one angle. So the question must inevitably become "What do you, personally, think?"
"We've all been dancing around the basic issue: does Data have a soul? I don't know that he has. I don't know that I have. But I believe that he has the right to discover that for himself..." - JAG Capt. Philipa Louvois, Star Trek: The Next Generation, Episode 34 (or 2:09): "The Measure of a Man" (thank you, IMDB.com [http://www.imdb.com/title/tt0708807/], lol)