You forgot to mention the roaming stronghold, like KoToR and Mass Effect! I'm just kidding of course, you can always consider a spacecraft where you have all your crew/party or inventory management a stronghold.
OT: It really doesn't matter to me, I like adventuring, I like stopping in towns, and I like having a base of operations as well. Adventuring and building up a roving party feels awesome, like you're pulling together a force to be reckoned with, inspiring folks to follow you to a greater cause.
But having a base to plan, regroup, reinforce and strengthen is also pretty cool. Somehow, I feel that in games where you have a home town, it's kind of a cliche for most people in that town to be against the protagonist, and it isn't until the end of the game where you've proven yourself that the initial opposition turns to support. Just a feeling I get, but I'm sure I could pull up many examples of that if I tried (first that comes to mind is Heroes Quest 4, which I replayed recently, and that came out in 1994!). Others that come to mind are Neverwinter Nights, and now I can't remember if it was Titan Quest or Dungeon Siege.....