Wow, people didn't get the symbolism of the Renaissance in the trailer? It's obviously meant to portray the futuristic period Deus Ex 3 is set in as one of innovation and great change, whether good or bad, basically making it a 'second Renaissance.' Honestly, it's not even that deep.
I seem to have liked Bioshock for a completely different reason then he said, I was more focused on how they took a very complicated subject, Ayn Rand's Objectivism, and managed to still use it as an excellent philosophical background without dumbing it down too much. Say what you want about Bioshock, but there's not a lot of games that are able to intergrade an entire philosophy into its story (case in point: the entire game's theme seems to be 'a man chooses, a slave obeys' one of the pillars of Objectivist philosophy). I eagerly await the Michel Foucault FPS.