I hope they don't skimp on the skeletal animations for male/female characters this time. It felt so lazy for them to just reskin femShep over the male skeleton, and looked so wonky. It was like she had space-scurvy, and I always felt like giving a good "arrr" everytime she ran. Especially on the Normandy. Also get rid of the head tracking lunacy. There were times I swear Shep was doing a Linda Blair/Exorcist impression when running by crewmates who happened to be chatting in the background.
Stoked about the Mako though, I loved how squirrely it was to control (except in missions where you could fall and fail). I tried many times to pull off some vert tricks like it was a skateboard, and while I didn't always succeed I did have some funny as fuck moments.
I'm a bit disappointed there won't be any racial options, but if that sacrifice means we'll get a decent game then I'm fairly forgiving... that better mean the game is good enough to hold up on its own. Also I can deal with a side-story taking place during the Reaper conflict, I always enjoy learning about people who aren't directly involved in the "must save the universe" plots. Its nice to be a regular Joe/Jane. Honestly I'm sick of having to be the world/universal crisis management team all the damn time. Smaller scale stories sometimes feel more personal, more easy to relate to.
I feel the same way about RPG's, and I've tried to avoid that stereotype as a DM, where the heroes end up saving the world/multiverse. I feel that in RPG's, the best stories are the ones where the heroes might be the badasses of their corner but are just another cog in the machine, that they can't massively affect (hah!) the world at large. It doesn't diminish their accomplishments, but it drives home the true meaning of mortality, that they're not all-important and irreplaceable. I honestly don't believe there's only one man/woman/team that can solve the world's problems. I like escapism, but there has to be some grounding for it.
A good example to me is from the No Mans Land arc from the Batman comics, where Superman tries to come in and "save" Gotham. Batman meets Supes and tells him straight up he isn't needed or wanted there and that the blue Boy Scout isn't the (for lack of a better phrase) "hero that Gotham needs". Supes tries to get things fixed, but even though he technically succeeds in fixing a power station, the people reject him and he crawls back to Bats, properly cowed where Batman basically says "Told you."
No matter how strong you are, you can't fix everything.