I'm a callous, arrogant, antisocial, misogynistic bastard who tends to view his fellow human beings as scum to be eliminated and/or resources to be exploited. You're scum if you go against my opinions of an ideal society and you are of no use to me. Some psychiatrists might argue that these are problems, but I do a pretty good job of pretending to be decent.
As for problems that actually adversely affect me from time to time, I usually don't notice or don't care about the feelings of others. For example, I once asked a young lady in front of the whole class if she was pregnant. It made sense to me, for she was of a rather stout build and wore an unflatteringly tight cotton dress. When she saw me staring at her and waved coquettishly, I asked, so she would not misinterpret it as interest in her. I knew she'd be somewhat offended; I did not know she would start crying and run out of the class. I said sorry out of custom, but didn't really feel bad about it, for if she didn't want to be asked such a question she wouldn't have worn that dress.
I don't know if this counts as a personality flaw, but I'm terrible about remembering people, probably because I consider nearly everyone without my close family and circle of friends to be of little or no importance to me. Even my so-called friends are ephemeral, for I never go out of my way to associate with them, and all the friends I've made in the past I've moved away from, have never seen since, and wouldn't really care if they all died. Really, the only reason I have friends is because I want something from them, like players for D&D (they never showed up anyway).