Cripple the wings. They become incredibly slow after that. Then keep picking them off in the distance. Recommended perks: Entomologist, Concentrated Fire, Hobbler. Wings count as legs for insects. Boone or Arcade can pick them off in the distance, ED-E's laser fire thing is very useful against bugs too.
For melee characters, let your companions do some distant damage, and then use turbo or the turbo implant to attack them quickly.
For melee characters, let your companions do some distant damage, and then use turbo or the turbo implant to attack them quickly.