Fallout 3 items you can't do without...

[fedpayne]

My female character has
Red's bandana
Reilly's Rangers Armour

The Terrible Shotgun (for shootin' down Ferals)
Harkness' Plasma Rifle (for shootin' down verti-birds)
Alien Blaster (for shootin' down EVERYTHING)

My male character has
Lincoln's hat
The power armour from Fort Constantine
Honest Abe

Lincoln's Repeater.

Space Lincoln will have his revenge!

 

[Octorok]

I hunt Deathclaws for a living in my game - I need Winterized T51-b, Alien Blaster, Dart Gun, A3-21's Plasma Rifle plus many, many other named weapons because I collect them. Also a few hundred stimpacks, and over two thousand of the main ammo types each.

 

[The Maddest March Hare]

Merc Veteran outfit. I just think it looks cool.
Headwrap. See Above.
Rock-It Launcher. Because launching toy cars at a giant green creatures nads has been, and always will be, the funniest thing ever. Except getting a Teddy Bear headshot. Cute'n'Fluffy deathray, engage!
And the Pre-War hat, because then I can pretend I'm Yahtzee. I'm really surprised Burke never featured in his Fallout review..