TB, Jesse Cox and Husky are the ones I always watch. TB's got really interesting videos, Jesse is pretty much the only LP'er I can stand, and they have a collab show on Terraria which is my favourite gaming series by far, they're really funny together. Husky does 100% starcraft commentary though, so unless you like that stuff he's not going to be interesting.
I also watch the yogscast, but I really don't like their main series like Shadow of Israphel and Tekkit. Simon and Lewis are funniest when they're just fucking around, but they try to script and act those 2 series and it gets really awkward since it's painfully obvious that everything that happened was planned out.