See, I have a cure for that issue. I use very carefully customized button layouts to help transitions. So, barrier in BB, shield in uniel, FD/blitz in Xrd, Vanishing guard/roll in N+ and Homing in AH, all these are assigned to L1. Furthermore, any 2button grab game always will be made such that grabs are doable by hitting square and triangle, (the exception being AH with its odd grab input) and any single button grab game will be made such that the grab is O wich is my heavy slash button.
By doing this before anything else, you learn to play the game with the new button setting and it won't be weird to transition. The important thing is to preplan it such that you do not unlearn muscle memory and to be creative with button leniency. For example, UNIEL is 4 buttons but my circle is actually my grab macro because I wanted D to be on L1 cause it acts as a utilty button and grab is something you wanna OS with an AA so instead of hitting 3 buttons, the O macro lets me do it with 2 while being familiar due to bein on he Xrd heavy slash button at the same time. Also if you do a super with the grab macro the super takes priority over the grab so that helps too since hitting L1 for supers would feel weird.
Little things like this can go a long way towards how fast you learn and how easily you transition between games.