Funniest game you know

[Vortigar]

Pokemon Yellow, pissing off Pikachu never gets old.

Blood... (1 & 2)
Good, bad, I'm the guy with the gun.
This is MY boomstick!
Let's see how this one blows up.
Excellent use of colour, the composition is but lacking.
I hate mimes.
It's howdy doody time kiddies, the bad man is here.
Heeeeeere's Caleb!
How long do you think I will tolerate your existence?
Through the lips, over the tongue and passed the gums, look out tummy, here I come.
snf snf, somethings burning.
Meat milkshakes, my favourite flavour!
Hello, Mr Caal-eeb, have you ever been or are you currently a character in a video game? wtf?
I love the smell of blood in the morning.
What we have here is a failure to caogulate.
It burns, it burns, Aaah, Oooh, Aaah!
*Wilhelm Scream
etc.
etc.

And then there's Fallout 1 & 2.

 

[ExileNZ]

Curse of Enchantia
Sacrifice
Haven't played Psychonauts or Portal yet (hangs head in shame)
Full Throttle
Space Quest 2
5 Days a Stranger (sudden, retarding brain injuries, anyone?)

Yeah that's more than three...

 

[Cab00se206]

Return to Monkey Island (That's Monkey Island 4)
Dear god Guybrush is hilarious.

Also HK-47 had some amazing lines.

 

[Lord Krunk]

Portal, Psychonauts, Conker's Bad Fur Day.

 

[Splitter]

The Timesplitters series had some pretty funny moments.
All the drunks in it were usually pretty good.
And all the times standing outside a room and hearing one obviously gay guard coming onto a scared guard inside it.
Everyone's reaction to "It's time to split!"
Theres loads more in there too.

 

[Beerish]

"I only wanted...to be loved"

Timesplitters had some good moments, more so than any other games I've played.

 

[rocky1007]

Portal, Psychonauts, and, for one of the funniest Force tricks, KOTOR II. You can do the mind trick on a guard and he will take a shortcut by fallng off the space dock.

 

[Simski]

Portal is simply the king of kings when it comes to humor.

I also liked Dead Rising.
It had a kinda twisted humor, you could use all kinds of funny stuff as weapons.
Using a bowling ball to throw a strike on a bunch of zombies, sticking a shower head into a zombie and see their blood pour out of it til they fall down and die, and riding over zombies with a lawnmower, are all excellent fun.

 

[Labyrinth]

Smacking them about with handbags. Very slapstick.

 

[Telekinesis]

I'll have to go with the crowd here and nominate Portal & Psychonauts.

Otherwise, the Phoenix Wright [And maybe Apollo Justice too. Just maybe] series has some funny references/lines.
It makes a game that would otherwise be "serious business" much more interesting.

 

[Madaxeman101]

Conkers bad fur day on the n64

 

[rakdosleader]

why has no one said the game run like hell. You could have a bawls energy drink while you get eaten alive.