For me, it's MOST of the games that come out of Japan. I often care little about the story and characters because, even if they may be "compelling" and well written and acted, the cultural differences are great enough that I generally find them to be distasteful to associate with for long periods.
In other cases, such as your average JRPG, even were I to enjoy the story, the simple fact that I don't care for the core combat mechanics that take up most of the game combined with the sheer amount of grinding one is expected to do means I'll probably never see such a game to the end.
Of course, I can recognize that even though many of these games are openly hostile to my pursuit of fun, there are often millions of people who completely disagree. As such, I can assume that the very things I do not like about many of the games from Japan are the very things that the fans enjoy.