I got walking pneumonia in fifth or sixth grade and clocked in the 150+ range of Final Fantasy X in about three weeks -- I think I got every ultimate weapon except one or two, all the Dark Aeons, and some other goodness; I remember pummeling the last boss to pieces, specifically using Lulu's "1-MP cost", "double cast", and "Ultima" for insane damage round after round. Weirdly though, when I went back to replay the game, I did horribly.
Most recently: Persona 4. Probably my favorite JRPG of all time, and I lost the memory card with my 150 hours of game time. That right there is what we call bereavement.