There's games that I refuse to see through to the end and games I refuse to play flat-out.
One game that springs to mind that I refuse to see to the end is Jericho (Clive Barker presents a Clive Barker game written by Clive Barker). A game with muddy visuals and mediocre game play, turned from a dull game into an annoying one thanks to the characters in the game. Ten minutes in, I've never felt so much anger towards a fictitious character in my life. The characters are like a Gothic diversity group, each horrible beings and have come together to spend time insulting each other and being generally annoying. I'm not sure what moment was the final nail in the coffin, if it was the blatant homophobia or the schizophrenic girl who tries to come off creepy and instead comes off as pathetic. Part of me wished the character you played at the start was the only one who survived rather than died near the start. I also wish for their spirits to be flayed and their bodies picked clean by crows, among other things that I could go all day about. They were simply the worst characters I've ever encountered in a game.
In terms of games I refuse to play at all, it would have to be Bayonetta. When I first heard of it, reminders of Dead Or Alive: Volleyball sprung to mind. I can endure some sexualisation, but Bayonetta crossed it for me. When the only defining characteristic of a character is their sexuality, then something has likely gone wrong. I've heard it time and time again that her sexuality is empowering rather than hindering, as she embraces it and uses it happily rather than does it to pander to their over-weight teen audience. If her, as a character, was the only problem then I'd probably try it out, but trying the demo I just grew bored and tired as the words "Devil May Cry" kept pulsing in my head. As much as people claim otherwise, trying the demo left me feeling "Devil May Cry, but it's sexualised for men and is absolutely confusing". To me, nothing was enjoyable game-play wise and Bayonetta embraced her sexualised nature a little too much for comfort.