I support used sales, if the publishers want to get rid of the GameStops of the world, set up your own damn used game shop, give incentives for gamers to sell their games there, like some kind of exclusive DLC code for their next game, or even better exchange rates would get people going there instead of anyplace else in my opinion. It's a part of capitalism, and like it or not, the world is becoming more capitalist.
Another point would have to be that I take new sales over used if I feel a game is worth 60 bucks, if I don't know anything about, there's no demo, and I can't find anything really substantial about it beyond "prettier colors, more engagier gameplay, strongier character development than that piece of shit those guys did", they lose a sale, I much prefer to have an idea of what I'm buying.
On the subject of pirates, I think alot of it comes back to a mixture of devs/pubs/etc./Idontgiveadamns, not putting out some kind of demo for it, laziness, and cheapness. Because of a mindset that alot of people have with "I've already got this free copy here, why should I go out and buy something that limits what I can do?"