Sexiest thing I've ever read! XDCarbonyl said:Aldolases are pretty badass, but if you're looking to synthesize something (and not just expressing it off of a plasmid in culture to purify), it's cheaper and easier to go with acid and heat (or something more complicated for stereocontrol), because proteins are a lot of work to purify and have specificity to their normal substrates. I'm slowly coming to love isomerases and thioester intermediates, they are fun. I'm a protein mechanism kinda girl these days. But I do enjoy organic synthesis, it is FUN AS HELL. Hetero-Diels-Alder reactions are SEXY. And also ZOMG biologically stable ylides bring me no end of joy. Silyl-chemistry is pretty excellent, lets you do all sorts of clever things.
SckizoBoy said:Sexiest thing I've ever read! XDCarbonyl said:Aldolases are pretty badass, but if you're looking to synthesize something (and not just expressing it off of a plasmid in culture to purify), it's cheaper and easier to go with acid and heat (or something more complicated for stereocontrol), because proteins are a lot of work to purify and have specificity to their normal substrates. I'm slowly coming to love isomerases and thioester intermediates, they are fun. I'm a protein mechanism kinda girl these days. But I do enjoy organic synthesis, it is FUN AS HELL. Hetero-Diels-Alder reactions are SEXY. And also ZOMG biologically stable ylides bring me no end of joy. Silyl-chemistry is pretty excellent, lets you do all sorts of clever things.
Still, I remember doing some carbohydrate chemistry, and replicating what would normally be a twelve step synth takes about thirty enzymes to carry it out. But for all that, awesome yields... ultimately I always ended up with about less than ten percent after a six step retro-, if I was lucky... :/ Rate of turnover, clean reaction, ease of product purification... and chiral-control, great deal if you can get enough of it.
Anyway, I'll try to weave Michael additions into anything... delightfully simple and elegant. Though, when you mention stable ylides... never heard of an enzyme mediated Wittig reaction (first thing that came to mind...).
And since we've gone off-topic, how's about we talk about endogenous opioids and calcium ion cascades... that's related to sex, isn't it?!
(And damn me, the memories of neurobiology 101...!)
I love sex. It is one of my two favorite activities.The .50 Caliber Cow said:I enjoy sex. A lot. It is a big part of my life and I openly admit that. Some people call me a slut because of that. I dont care.
How do you view sex in your life?
See, I say, if you feel the need to justify your sex life something's up.Bara_no_Hime said:I love sex. It is one of my two favorite activities.The .50 Caliber Cow said:I enjoy sex. A lot. It is a big part of my life and I openly admit that. Some people call me a slut because of that. I dont care.
How do you view sex in your life?
And "slut" is just a word used against people who enjoy sex by those who can't get any.
captcha: "enjoy life" - indeed I do!
I cant tell, are you being serious or mocking me?Monoochrom said:Sounds like a reallty healthy relationship.
That, and the fact that SHE said the only reason she will ever have sex is because she wants children (if it makes any difference, she has Aspergers too)Liquidacid23 said:I would assume that's because you have Autism thus initiating intimate relations is a lot of work![]()