Aw, why would you kill such tiny creatures? Even the dangerous ones need love.
Usually the annoying critters would crawl around the floor and I scoop em up and throw them outside. The interior of my humble abode is no place for such an animal, after all.
Flying bugs I catch with stun spore + pokeball combo my hands, and I let them go outside, or have them crawl on me after I catch them.
Some are hazardous to handle, but I remember I am larger and have tools at my disposal. Spiders on the other hand may bite me, but they deserve to stay. They get grub by eating other insects, in exchange for keeping the house pest-free.
Spiders are always welcome.
Fun Fact: Did you know there is an estimated 10 quintillion insects inhabiting the planet at any one time?
That's a lot of love to give, or squishiness, depending how you look at it.