Mikejames said:
Well, making sure Wrex doesn't survive ME1 is a start.
Then again, turning on him in ME3 might have even worse results.
Cloake said:
First thing that comes to mind is the suicide mission. Go through it with complete disregard for your comrades, letting them get picked off, and then at the end, hand the Collector base over to Cerberus.
Handing the Collector base over to Cerberus had negative consequences? I just recall the salvage providing more war assets during the final assault on TIM's base.
If Wrex is alive, the Salarian matriarch bribes Shepard(not sure if you have to accept the bribe), which IIRC requires the original Council dead, and stop Mordin from curing the genophage, Wrex will confront Shepard on the Citadel in a very Krogan-like manner. Shepard ends up killing him/allowing him to die. This has the lowest potential score for the Krogans, as well as you losing the EMS boost from having Wrex as an asset.
I don't know how much EMS you lose because of it, having never done this in a playthrough myself.
Also, for the lowest EMS, you need Mordin, Tali, Jacob and/or Jack(and/or possibly Legion) as the two survivors on the suicide mission. Anyone else will give you a point gain. Those are the only four that are taken care of in 3 in a manner that keeps you from gaining points. Thane is killed in 3, but if he's the one who attacks Kai Leng, Kirrahe will add points to your EMS, so Thane needs to be dead in 3 so that Kirrahe dies as well. For Jack and Jacob, just don't do their missions and they end up dead. For Mordin, you're stopping the genophage from being cured, so will take care of him yourself, and IIRC, the Quarian Fleet is worth more than the Geth fleet, so it's better to let the Geth kill the Quarians, which takes care of Tali. Although, this is assuming that Garrus and Tali, being squad-mates in 3, add to your EMS, which I don't remember if they do or not. If they don't, you could always just keep Garrus and Tali alive. Makes you feel less of a jackass when sabotaging the genophage curing.
Oh, and a few of the side quests in 3 can lead to a lower EMS, such as not letting the Turian at the space port stay with his Asari wife. If you let him go, it has no impact on your score, but if you let him stay, it raises the Citadel's security score. Collecting and turning in the various drop-off quests is also a no-go, as most, if not all of them add to your score by bolstering the various fleets.
Your import needs to have few resources accumulated during 2. Having a lot of ore will add to your EMS, as will upgrading the Normandy in any way, and that includes the Medbay.
You need to let all of the Normany's crew be turned into goo in 2. And you have to recruit Chakwas to your ship, as well as Kaiden/Ashley. If you don't, Chakwas and the Wonder Twins act as war assets, increasing your EMS.
As far as I remember, the Collector ship has no bearing on your EMS, nor does handing over Legion to Cerberus or recruiting him.
There's a few more things you can do, I believe, but I'm drawing a blank on it. For worst possible outcome in a story sense, I'm gonna have to agree with RedEyesBlackGamer, and say Wreav + cured Genophage - Eve = bad times.