Let's see, where to begin with...
Let's start big - Voormas from Mage: the Ascension. A very quick description - Voormas belongs to an order which strives to keep the balance of life and death (it's more complicated, but that description should work. The problem is, that due to the close brushes with death they have, they are very likely to build up Jhor - sort of energy that may end up warping the thoughts of a person. Normally, Jhor sort of makes a person extremely fixated on death and eventually either a complete nihilist or an emotionless murderer. Voormas is long past that point but also he's a bit special - he is extremely afraid of death and dying himself. So, what does a person
heavily afflicted by Jhor do when they are afraid of dying? He sets out to find a way to eliminate the very concept of death itself. Also, meing a powerful mage, long ago, at around the start of his journey, he poisoned necromancy itself, so practitioners tend to subconsciously try and tear down the wall that separates the world of the living and the dead.
So, moving on to other World of Darkness characters - there is no shortage of them. Let's go with Darius, from Werewolf: the Forsaken. Yes, he's a werewolf. In the games, if you don't know, they have a society of sorts - they aren't necessarily allies all the time but...well, pretty much work like humans, basically. Except they gather into packs. Darius managed to get his whole pack killed horribly. He is a real sadist and enjoys killing painfully and most of all prolonged. He went as far as creating a new fighting style against werewolves, which relies on causing them lots and lots of pain (they are hardy and regenerate fast, but if you break an arm and keep itat an awkward angle, for example...). He also managed to get a spirit blessing that basically protects him from harm, as long as he is causing harm, which fits nicely...until the payback, that is. See, he isn't "immortal", the wounds just get stored away for a later time. And they could afflict his fellow pack members, too, instead of only himself. That's what happened one time - too much punishment suddenly lashed back at him and killed everybody, leaving him the only survivor.
Moving on again, Mage: the Awakening has so many good ones, I don't eve know where to begin. There is a guy who tries everything,
everything to continue his family line. There is the Fury - a creature that normally helps people achieve their fates...only she has lost her ability to
see the fates, so she wanders around sort of blindly, homing on the "strongest" fate and then making it up as things go along. Then there is Metathron, who is a messanger of Fate, inflicts prophecies of doom and ruin to those who seem "worthy". Only, he never actually knew who is "worthy" or why the prophecies were needed, so he's just ruining lives at random. There is an axe that has actually gained sentience...but it's from the Dark Ages and was used to slay "witches", so that's all it wants to do. The axe also has very warped perception of what a witch is, and wouldn't hesitate to share it with whoever holds it - be it the alleged witch's friend or even family member... One of my favourites is a mage who in the Victorian age decided to go more science-y and replaced her brain with a clockwork mechanism, which turned her into an amoral abomination, doing all sorts of fucked up experiments for the lulz science. She was eventually tracked down and killed, but the clockwork brain remained and is now part of a travelling exhibition of interesting artefacts - very few, if any, people know it's real purpose. Well, they quickly find out if they manage to activate it...which takes a quick tap, incidentally. At this point, the ghost of the mage appears and quickly turns everything into something worse than a horror movie set - pretty much any living thing, she'll lobotomize and stuff with random clockwork bits, turning them into little more than a zombie to help he with other "experiments", like lobotomizing even more people or operating on them. No anaesthesia, of course. That operates until the brain "winds down", in like an hour or so, all the "zombies" just fall dead, at the very best case they can be salvaged into nothing more than a vegetable - doomed to only live on live support. And aside from her, there was a mage that
meant well but ended up horribly fucking up all young people in a small-ish town. He was basically disgusted with that whole "teen pregnancy" thing and made it so all the local school students have no sexual drive...which is actually a
bad thing, since it's like a natural thing. Pretty much all the graduates end up with various psychological problems, a lot are just downright serial killers.
And aside from WoD, there is Johan Liebert from the anime Monster
He is extremely disturbing. Casually brainwashes people into suicide, or kills them themselves, or goes and manipulates mentally unstable serial killers into going after them. Nobody is safe. Well, only one guy, but the fact that Johan won't
kill him doesn't mean he's gonna be all right.
