Not at all. As BioWare have stated rather frequently, though the game is a sequel it can stand alone as just a game to pick up and play. But if you care a lot about story in your RPGs like me then it's something you're going to want to do. Mass Effect probably has one of the best stories I've seen in a so-called "action RPG".slowpoke999 said:Mass Effect 2
Then Bioshock 2
Then Aliens Vs Predators
Then Bad Company 2
Do i need to play the first Mass Effect to play the second?