I can't think of a specific game where there is a part I don't ever want to play again. But what does annoy me is games where it takes an extended un-skippable amount of time to start a new play-through/character. Fallout 3, Skyrim, Oblivion were all bad for this, or fps games that force you to do the "learn to shoot" mission every time. Fortunately I rarely replay campaigns on fps games. But for games that are single player based, those un-skippable intros become so annoying. At least in Oblivion you could save right before exiting the sewer, and therefore could load that save up, still change all your character info then exit. And Fallout 3 had something like that, except you could make some decisions in the vault prior to leaving that have repercussions later on. Skyrim is the worst for this for me. I have a save before the legion calls your name to be executed, so I can load that to skip the opening wagon ride sequence. However, I still have to do the entire run from the dragon, fight your way out the underworks. Even speed running it, it still takes 10 minutes. It's really annoying, since I enjoy making new characters from time to time.