I really don't find much replay value in games, because your character build rarely makes that much of a difference. I mean yes, hitting someone with a sword vs using spells, or being a soldier vs a vanguard or yadda yadda yadda. But the character doesn't really change the story.
No matter if your a Nord warrior or a Khajiit thief, chances are good the StormCloaks and the Empire will still be a war, you'll still need to kill bandits in towers, and you'll still need to kill giants for Thanes and you'll have to grind Smithing and Enchanting all over again
Or no matter what Shepard you are, you're still gonna fight Saren, the Collectors, The Reapers. You'll still spend way too long on the planet scanning mechanics in ME2 or endlessly searching every planet in ME1 for the last Asari token or the Citadel for the last Keeper to scan. And running across the galaxy doing the same boring squadmate side missions and responding to Aria in the exact same way each time.
Or even Dark Souls where the character class can seriously change your playing style; what are the odds you still have to go to Blight Town or fight fuck-off big skeleton daemon knights? Or that you'll die alot?
I get that some people can put up with the grind, but I seriously can't. I even have a little thread going right now on getting bored with games. I mean when you think about just how much samey-ness there is between play throughs(roughly 90% the exact same I'd say!) the idea of wondering the Mojave or Skyrim all over again just to have the occasional different inconsequential dialogue option or to kill the same endless bandits in a slightly different way...I'm sorry, but no thanks.
I'd rather just YouTube the alternate ME romance scenes for pairing I enjoy than play through the exact same game 5+ times to just see a handful of difference scenes.