Depends on the game, naturally. If the soundtrack is vital (or simply awesome), like in a lot of my RPGs, fighting games, and visual novels, usually not[footnote]I have made occasional exceptions. The Gurren Lagann soundtrack goes surprisingly well with Smash Brothers 64, and I managed to slip <url=http://www.youtube.com/watch?v=cLBAFJWbd30>The Time Has Come into one of the climactic fight scenes in <url=http://www.escapistmagazine.com/forums/read/326.252998-Neutral-Drow-reviews-Princess-Waltz>Princess Waltz (Liliana's final boss fight), where it fit surprisingly well.[/footnote].
MMOs are usually fair game, though. I've actually been in the habit of listening to internet videos while playing those (I've been having a couple of LPs and recently DBZ Abridged playing while I played City of Heroes).
MMOs are usually fair game, though. I've actually been in the habit of listening to internet videos while playing those (I've been having a couple of LPs and recently DBZ Abridged playing while I played City of Heroes).