It depends on which looks better. In some games the females look better in other games the males look better.
I'm not sure what this says about me but the vast majority of the Champions I own and play in LoL are female. I didn't even notice until a while ago when it just dawned on me. I think the female art designs are just generally more
interesting when it comes to LoL...
I
Wonder
Why?
To be fair to them, Ezreal singlehandedly makes up for the male side of things. He's a true display of manliness!
Funnily enough I was a fan of MShep in the Mass Effect games. I found that FShep was always sounding slightly pissed in all of her voiceovers. Perfect for a Renegade playthough I will admit but MShep has more varity, especially in ME3 where the guy practically unleashed pure badass voice acting talent onto the game.
In games where you are forced into a specific gender I don't really care. Your character is your character.