I play on easy first, almost always. That is because I am more into the experience than the challenge and I value my time too much to play over a single segment more than three or four times. This is specially true for long games (like RPGs), where the option to replay the game on a lower difficulty if I get stucked is out of the question...
The only times I play games on higher difficulties is when I am familiar with the game or the franchise and I am just replaying it for fun.
The only times I play games on higher difficulties is when I am familiar with the game or the franchise and I am just replaying it for fun.