Poll: Have you ever had your sex chromosomes directly examined?

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Vault101

I'm in your mind fuzz
Sep 26, 2010
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you can test thease things?

Im pretty sure I'm 100% female

though somtimes I think I think more like a man...somtimes

and when I was a kid I hated wearing girly cloths because it just felt...[i/]wrong[/i] but I think thats more of a personality quirk rather than some depe gender related issue
 

Psykoma

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Nov 29, 2010
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CrystalShadow said:
The second is that it's a routine test for anyone about to be treated for transsexualism. Before they prescribe hormones, or even consider surgery, or do anything else at all, they again check this, to verify whether you may have some kind of undiagnosed intersex condition. (Because you're not supposed to treat a person with an intersex condition as though they were a transsexual - Kind of splitting hairs really, since the hormonal and surgical tools used in either case are pretty similar, but they are considered medically distinct situations, and the overall theory behind the respective ways they are treated is different, regardless of the practical techniques involved.)
I didn't have this done 0.o

The only medical tests I've had related to transsexuality were:
Before hormones: Whether the hormones would kill me or not
Routine since then: hormone levels
Before surgery: hiv, other blood-born diseases, hormone levels, will surgery kill me.

There were never tests checking my DNA.

I've never even heard of that being part of any routine, and I haven't seen it anywhere in WPATH's Standards of Care, do you have a link?
 

viranimus

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Nov 20, 2009
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Not certain but willing to take on female volunteers to perform the up close and personal test.


But in all seriousness. I see no need. Im pretty sure I can eyeball it.
 

Sokarred

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Dec 7, 2010
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People keep saying you can tell just by looking, but you would be surprised. When in the womb, everyone starts off as a kind of in between gender that leans towards female. Then chromosomes and hormones determine what gender you actually turn into. But there are syndromes and different stuff that can mess with your gender. For example, a person can be genetically male, but their body gets flooded with estrogen in the womb, giving them heightened female characteristics. Their testicles even stay inside their body, usually confused for ovaries.

I once read an article about a woman who went to the doctor because she could not get pregnant, and she never had a period. The doctor examined her and determined she was genetically male. Her family, husband, and all previous doctors and no idea that she was genetically male. Even more, the woman explained her problem was common in her family, with the no period and no babies thing among the women in her family. The doctor theorized that the other women in her family were also genetically male and that the condition ran in the family. Last point from article, the doctor decided not to tell her or any family members she was genetically a guy because the doctor didn't want to shatter the woman's self perception.
 

requisitename

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Dec 29, 2011
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No, because I really don't care. That sounds dismissive, but I don't mean it that way. I mean, I'm as close to 100% certain as a non-tested individual can be about what I am.. but if I'm wrong, it in no way impacts my life because I'm not looking to change anything.

Also, as CAPTCHA says: "life's too short". Haha.
 

Exile714

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Feb 11, 2009
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CrystalShadow, I think the reason people are confused is not because of the science, but because there is a logical fault in your concept.

Assertion: transgendered people cannot change their genetic sex.
Refutation (your premise): most people do not know whether their genetic sex is normal (XX/XY) or intersex.

Yes, there are people whose genetic sex is complicated but knowing one's genetic makeup does not change their sex. There is no logical link between the assertion that people cannot change their sex and the premise that people do not actually know their sex.

I think the underlying problem is that you are conflating sex with gender, possibly because you find sex (the biological configuration) easier to argue than gender (a combination of personal preferences and whether they align with societal norms). But transgender people, as opposed to intersex people who have a genetic abnormality, cannot change their sex. If you are XY but feel that your gender is female, or XX and feel that your gender is male, then you are transgender.

It sounds like you're trying to argue against someone who clearly does not understand what being transgender means. I think you do, but maybe you can't quite put it in terms which will be agreeable to this person and you're looking to overcome an argument which you cannot defeat.

Gender is about more than simple choice; there are ingrained feelings and emotions, some triggered by hormones and others by forces unknown, which guide us to our gender. Sometimes, be it through an intersex chromosome issue or some mechanism yet unknown, one's gender does not match one's sex. You can't change the sex, but you can alter the body to make it a better fit with one's gender.

I hope this helps. You're not going to win an argument with this premise, but in the end you shouldn't need to. I don't know if you're transgendered yourself or just trying to understand the topic better, but it's such a misunderstood topic that logic will rarely win against someone's preconceptions about it. Luckily, there seem to be more and more people who understand. Seek them out, and just avoid the topic if you can with those who don't understand.
 

CrystalShadow

don't upset the insane catgirl
Apr 11, 2009
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Psykoma said:
CrystalShadow said:
The second is that it's a routine test for anyone about to be treated for transsexualism. Before they prescribe hormones, or even consider surgery, or do anything else at all, they again check this, to verify whether you may have some kind of undiagnosed intersex condition. (Because you're not supposed to treat a person with an intersex condition as though they were a transsexual - Kind of splitting hairs really, since the hormonal and surgical tools used in either case are pretty similar, but they are considered medically distinct situations, and the overall theory behind the respective ways they are treated is different, regardless of the practical techniques involved.)
I didn't have this done 0.o

The only medical tests I've had related to transsexuality were:
Before hormones: Whether the hormones would kill me or not
Routine since then: hormone levels
Before surgery: hiv, other blood-born diseases, hormone levels, will surgery kill me.

There were never tests checking my DNA.

I've never even heard of that being part of any routine, and I haven't seen it anywhere in WPATH's Standards of Care, do you have a link?
I'm pretty sure it was listed among the many things they proscribed for the blood tests they gave me in the UK.

It may not be universal in all countries, but it does stem from the medical diagnostic stuff. I doubt it has anything to do with WPATH, but the DSM-IV does imply it.

http://www.genderpsychology.org/transsexual/dsm_iv.html

Note the following sentence: "The diagnosis is not made if the individual has a concurrent physical intersex condition (e.g., androgen insensitivity syndrome or congenital adrenal hyperplasia) (Criteria C)"

This means that according to the DSM IV, you cannot have a diagnosis of transsexualism and ALSO have an intersex condition. (They are mutually exclusive)

Therefore, testing for various kinds of intersex conditions are required as part of a diagnosis, and at least some of the tests for that are chromosome tests.

this paper discusses whether it is a test worth performing:
http://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2010.02130.x/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+17+March+from+10-14+GMT+%2806-10+EDT%29+for+essential+maintenance

But notes that it is quite common to do so. (or it would appear to. Getting access to research papers is a bit irritating.)

Though I admit I can't find a specific source claiming these tests are commonly performed, anecdotal evidence from most of the people I've talked to in person suggest they are, (Certainly in the country I live in...) because I routinely hear statements that wouldn't make sense unless a person had been tested.

Anyway, I did forget a major area where genetic testing was common until recently. Female athletes were routinely subjected to genetic testing. But due to ongoing pressure that's been discontinued.
 

Lunar Templar

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Sep 20, 2009
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Amethyst Wind said:
I didn't even know there was such a thing. Hmm, if it's free to find out then I'd be interested. many lulz could be had by dropping 'oh, by the way my genes are female-coded' into a conversation. Or many. Or just using it as a way to freak out the charity beggars who try to stop me in the street. I have lots of arrows in that quiver already but one more couldn't hurt.
this,

XD though know you have me wondering if the coding matches the plumbing
 

Payned

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Oct 19, 2011
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CrystalShadow said:
Payned said:
Quick thingy, having a monosomy/trisomy doesn't make you "intersex". Sex is determined by the presence of a Y chromosome and not by the number of X chromosomes. Of course you can have some genetic anomalies (such as with Klinefelter's Syndrome XXY), but it doesn't make you "partly the other sex". Just thought I'd clear that up, as it could possibly offend some people who read this thread.

OT I haven't had a formal test but we did look for barr bodies (which form when more than one X chromosome is present in a cell) in our own cells and I couldn't find any which means that I'm almost definitely XY.
Interesting. However, don't several of the known intersex conditions contradict the idea that the Y chromosome determines sex? That's kind of the whole point of the poll to some extent.

being 'partly the other sex' depends entirely on the definition of sex. Certainly if you state (as you do) that the Y chromosome determines sex, you get a very neat answer. It's just not one that really makes much sense, except as an extreme form of reductionism.

Since you seem to know something about the subject however, can you have an abnormal set of sex chromosomes without being considered intersex?
If so, what are the criteria for a person being intersex?

(Aside from which, as far as I understand the subject, It's not the Y chromosome as much as it is a specific set of genes found on the Y chromosome. Development along either path depends on genes spread all over the genome, most of which are shared between both sexes regardless.)

Anyway, since anything other than XY or XX is a genetic abnormality, why would that not constitute being intersex (genetically speaking at least).

(As to the poll, it's a separate answer because it's unusual, and because of the purpose of the poll, lumping in such things as XXY, X0, XXX, or anything else with the 'male' and 'female' groups would render the intent behind the poll largely meaningless.)
Yes I said that sex is determined by the Y chromosome to simplify things because I assumed that most people here wouldn't have a strong background in genetics. Apparently I was wrong :p But yes the TDF (testis determining factor - what determines your gender) is thought to be the SRY gene found normally on the end of the Y chromosome, so for almost all cases that equals the Y chromosome itself being the TDF.

With term "intersex" I was assuming you meant hermaphrodites, which people with mono/trisomies *usually* aren't, and so I just wanted to clear that up for those people.

Criteria for intersexuality? I haven't actually studied that, but as far as I know it's quite loosely defined and depends on the context (physically feminine male all the way complete hermaphrodite) and I don't think that there are clear deterministic criteria. But yeah, men with Klinefelter's (unless they have any other conditions) are very clearly male, and some don't even display any symptoms.

What causes true intersexuality/hermaphroditism? Once again, not my field so the most I can make are educated guesses. As the "default" for all human foetuses are female, I would assume that abnormal hormone/environmental mutagen levels (which yes could be exacerbated by genetic defects) could cause an incomplete shift towards maleness.
 

CrystalShadow

don't upset the insane catgirl
Apr 11, 2009
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OK. Thanks for the explanation, though the conclusion isn't entirely consistent with what I meant.

Exile714 said:
CrystalShadow, I think the reason people are confused is not because of the science, but because there is a logical fault in your concept.

Assertion: transgendered people cannot change their genetic sex.
Refutation (your premise): most people do not know whether their genetic sex is normal (XX/XY) or intersex.
Ah, that's an interesting interpretation. Unfortunately, it's not what I meant.

Stated in the same terms, this is what I meant:

Assertion: transgendered people cannot change their sex, because it is determined entirely by a person's genetics.
Refutation: Most people are quite certain what their sex is, yet probably have no idea if their genetic sex is normal.

To my knowledge, that's a different argument. It's not about whether you can change your genetic sex, but whether a person's genetic sex is actually even relevant.


Yes, there are people whose genetic sex is complicated but knowing one's genetic makeup does not change their sex. There is no logical link between the assertion that people cannot change their sex and the premise that people do not actually know their sex.
That depends on defining sex in a very specific way, which was the point of my argument. Not whether knowing your genetic make-up changes anything about you one way or the other.

As I said, the actual assertion I'm dealing with is: Sex is defined solely by your chromosomes. - But for that to be valid, you'd have to know what your chromosomes say. Otherwise this can't be a meaningful definition of a person's sex.
(How can you know someone's sex if the only trait it's dependent on is usually an unknown?)

I think the underlying problem is that you are conflating sex with gender, possibly because you find sex (the biological configuration) easier to argue than gender (a combination of personal preferences and whether they align with societal norms). But transgender people, as opposed to intersex people who have a genetic abnormality, cannot change their sex. If you are XY but feel that your gender is female, or XX and feel that your gender is male, then you are transgender.
Most people that argue the point I'm trying to refute also make the claim that sex = gender. (IE, both terms mean the same thing. Therefore, for the purposes of the argument I'm trying to refute, if sex is immutable, so is gender.)

Otherwise, I'm personally not convinced either way. Gender is unbelievably complicated, and certainly has several possible interpretations that imply not only that it is possible to change it, but in fact that it is quite trivial to do so.
(Assuming gender to be an entirely social construct with no direct relation to biology for instance, you can change your gender merely by changing your behaviour...)

It sounds like you're trying to argue against someone who clearly does not understand what being transgender means. I think you do, but maybe you can't quite put it in terms which will be agreeable to this person and you're looking to overcome an argument which you cannot defeat.
(sorry if this is confusing. - I clicked 'post' accidentally before I was done.)
Pretty much true, really. I know the chances of actually convincing anyone are quite remote, but I tend to try anyway. You never really know what people will respond to.

Gender is about more than simple choice; there are ingrained feelings and emotions, some triggered by hormones and others by forces unknown, which guide us to our gender. Sometimes, be it through an intersex chromosome issue or some mechanism yet unknown, one's gender does not match one's sex. You can't change the sex, but you can alter the body to make it a better fit with one's gender.
As I said, there's many possible interpretations of what sex and gender are, which vary depending on what any given person's views are.
Generally, the most common ideas about it tend to assume that sex & gender are almost interchangeable concepts, and they don't get into much detail about what defines either because it's taken for granted that there aren't any people that don't fit the basic assumptions, so why bother being clear about the actual definitions?

I hope this helps. You're not going to win an argument with this premise, but in the end you shouldn't need to. I don't know if you're transgendered yourself or just trying to understand the topic better, but it's such a misunderstood topic that logic will rarely win against someone's preconceptions about it. Luckily, there seem to be more and more people who understand. Seek them out, and just avoid the topic if you can with those who don't understand.
It does help. Though clearly I'm not getting the right point across regardless of whether the argument is a good one or not.

Thanks for clarifying that though.
 

Bara_no_Hime

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Sep 15, 2010
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Never been tested.

However, the fact that my uterus has been proven functional seems to be compelling evidence that I am XX.

Although I don't know enough about some of the intersex possibilities to be sure - are there intersex options that can successfully get pregnant?

Oh, and OP - I have no idea why everyone is being so defensive. You pose a good question.
 

00slash00

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Dec 29, 2009
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i have never been tested. i cant see it changing anything though. i was born a man but identify as a womin, thus i am a womin
 

CrystalShadow

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Apr 11, 2009
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Bara_no_Hime said:
Never been tested.

However, the fact that my uterus has been proven functional seems to be compelling evidence that I am XX.

Although I don't know enough about some of the intersex possibilities to be sure - are there intersex options that can successfully get pregnant?

Oh, and OP - I have no idea why everyone is being so defensive. You pose a good question.
It is pretty good evidence, yes. XD

It's just that I started this from an argument that implied genetics matters more (and over-rules) the rather more obvious traits a person has. (IE, what are their sexual organs like... Can they successfully get pregnant... Can they get someone else pregnant? What does their overall appearance suggest... Their legal status... Their social groups, etc. All of the stuff that is far more visible than whatever genetics they may or may not have)


Anyway, up until recently I actually would've thought most intersex conditions result in infertility. especially if they involve your physical appearance being radically different from your genetics.

Of course, then I found this: http://www.gendercare.com/library/italiano_paper3.html

While I'm not entirely sure it's a reliable source, it surprised me to even hear mention of it, since it implies a person with XY chromosomes, who appears female, has a functional uterus, and even has semi-functional ovaries.
That's certainly far more of an extreme reversal than even I was expecting to ever hear about.


As for people being defensive... I guess people don't like to have something fairly fundamental to their identity questioned?
It's not like I'm saying it's very likely that you aren't what you think you are.
Merely that I don't think the majority of people actually know.
 

Bara_no_Hime

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CrystalShadow said:
As for people being defensive... I guess people don't like to have something fairly fundamental to their identity questioned?
It's not like I'm saying it's very likely that you aren't what you think you are.
Merely that I don't think the majority of people actually know.
Indeed.

And I quite agree - your genes don't matter nearly as much who you choose to be.

People in this thread need to calm down and remember that if you think you're male - you're male for all intents and purposes. Don't sweat an extra chromosome here and there.
 

longboardfan

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Jul 27, 2011
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I am very confused. You seem to be implying that I could have predominately male attributes such as penis and testis (with successful sperm production: not sterile), but be actually XX dominant? What? Well considering that I'm not XXY and sterile, or dead at infancy. I also don't have downs syndrome, turners, Klinefelter, or many of the other chromosomal disorders. I survived birth so I don't have trisomy 8, trisomy 9 and trisomy 16. I didn't have Cri Du Chat (disorder of the 5th). So I'm curious as to just what your point was. Are you trying to (in a very round about way) trying to argue karyotype over phenotype? Or are you just being stupid?
 

Scabadus

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Jul 16, 2009
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I'm shocked and dissapointed that nobody's made the "very large peice of evidence" joke yet. For shame escapist, for shame.

OK lesson time: the X chromosone actually contains all the information for both sexes. Yes, if you're female you have a full and complete set of genes for growing a penis in every cell.

Huh... that was a very poorly constructed sentance.

The Y chromosone is (and pease do feel free to laugh) fairly short and unimportant, containing little of any worth. For the most part it consists of genes that activate the male parts of the X chromosone and repress the female parts. For the advanced student, there a few Y chromosone genes that make totally unrelated protiens, but as far as each are concerned in determining gender, all Y does is flick the Male/Female switch on X.

Why did I go through that? Well, to prove how your body is your DNA, it can't be any other way. If you are male then you have an XY chromosone confiiguration, you MUST have one X to provide the base code and one Y to alter the X chromosone in the right way (for those people out there who are... well, like me, then yes technically it's possible that the X chromosone could have spontaniously mutated to create a male human, but the chance of that happening is so small that the amount of 0s involved would probaby crash the internet or something equaly as spectacular). Likewise if you're female then you MUST have and XX configuration, because a Y chromosone would have altered the X and made you male (and you need the second X for some more complicated reasons involving protien levels, I won't go further into it but if you're healthy and female, you have both Xs).

As such, looking down while naked provides as good a check of your gender-determining DNA as looking in a mirror provides for your eye-colour-determining DNA. Yes, you could ask the question "what if you have green eyes but your DNA actualy codes for blue eyes?! You're not who you think you are!" but that's not going to happen. If you have green eyes, you have green-eye DNA. If you have a penis (and none of the uncommon but very obvious genetic diseases associated with strange XY chromosone configurations) then you have one Y and one X chromosone.

Can you tell I'm studying genetics? I'm very subtle about it.
 

tthor

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Unless there is something big I am missing here, I feel like this is a a kinda silly/pointless topic (if there is something big I am missing here, like a regular occurrence of people being born with a functional penis and testicles but genetically XX, then I would appreciate it if it said in the original post.)

If you were trying to get at the topic of things like transgender and gender changes, and whether that defines your gender, I think you already confused and derailed your own topic with how you phrased it
 

direkiller

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Dec 4, 2008
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CrystalShadow said:
Yet, how many people actually know what their chromosomes are? You say you're inferring an answer
Well yea your 23 chromosome set determans what organs form (not what gender you identify yourself as just what organs form). Those organs have spcific genders assigned to them. I personly think it has more to do with mental mindset but a baby can't articulate or even underdstand that mindset so organs are a good place to start and by extension the chromosome.


I hope you take this as constructive criticism but it appears your approaching this from the view of a flat earthier, or creationist. That we cant trust scientist or High school biology that tells us XX forms Female genitalia(ovaries,functional mammary glands,ecd.) and XY forms male genitalia(prostate,testicals , and so on). that unless we test our own genes we cant use this criteria because we cant know if that's true for every person. Yes I realize that your trying to convey that people are more then the organs there born with but can you try and do it in a way that dose not boil science down to "Well you don't know because you never tested it".