Just look at my history in the Mass Effect games and Fallout 3.
I'll start with FO3. To put it plainly, I did everything to be as far off the Good Karma deep end as possible. Keeping Amata's father alive then making her Overseer of Vault 101. Taking President Eden's Modified FEV and giving it to Elder Lyons. Activating Project Purity with no toxins in it(though I usually had Fawkes activate it instead of putting my neck on the line; only recently did I choose to fully embrace the idea of the "Lone Wanderer" and do it myself). Nuking Adams AFB from orbit with the Enclave's own satellite. Wiping out the Slavers of Paradise Falls(actually quite profitable, if you take that Lawbringer perk; you'll be swimming in caps from fighting the Enclave too, so there's really no reason to NOT go Good Karma and be the richest goody-two-shoes in the Wasteland).
As for Mass Effect, it really applies across the entire trilogy that I went full Paragon everywhere I could. My Shepard was a Colonist/War Hero, having grown up on a remote colony, then single-handedly stopping the Skyllian Blitz dead in its tracks. I chose to save the Rachni Queen on Noveria, tried to save as many of the Feros colonists as I could(mostly by ordering my squad to hold back and only using melee if I didn't have any grenades left), and I ended up leaving Alenko at the bomb site on Virmire to save Kirrahe's team(which happened to have Williams with them; BioWare seriously dropped the ball on that one, not allowing you to say that you're trying to save the Salarians, NO, it's gotta be about the Normandy's crew all the time). I also had Anderson punch out Udina to release the Normandy, then chose to save the Council when Sovereign attacked the Citadel. Anderson became a Councillor because of me, too. All this is just the first game, too.
ME2, there's only one Renegade interrupt I take, and it's surprisingly NOT the Wyrlock Clanspeaker on Tuchanka, it's the Eclipse mercenaries at the start of Lawson's loyalty mission. Outside of that, I'm still just as far off the Paragon end as before, saving Maelon's research into a genophage cure during Mordin's loyalty mission, convincing Jack to let Aresh go in her loyalty mission, convincing Garrus to let Sidonis live in his loyalty mission, handing Ronald Taylor over to the Alliance in Jacob's loyalty mission, killing Morinth in Samara's loyalty mission, and the crown jewel of that entire game being blowing up the Collector base to keep the Illusive Man from salvaging it(plus I kept my whole crew alive through the entire Suicide Mission on top of that).
ME3, it basically starts with me curing the genophage and uniting the turians and krogan. I somehow managed to get the Charm option to negotiate peace between the geth and the quarians, too. Everything I did, I was being as Paragon as I could be, including saving the Rachni Queen(again). But in the end, I decided that freedom from the Reapers' influences was more important than anything else, and I blew the power conduit to end the Reapers for good. I can only hope that the races of the Mass Effect setting use this opportunity to advance without the Reapers' influences, and bring about a new golden age of peace.
So yeah, it should be pretty clear where I stand. But don't ever let anyone tell you that being good means being soft. Even if my Shepard was the nicest girl in the galaxy, you need to remember that she's still the deadliest thing in it.