I guess I generally prefer kinetic with some variety.
That being said, do you mean lasers, as in directional optic beam weaponized as means of delivering thermal damage or vague "pew pew" Star Wars blaster-style weapon?
As for variety...:
Explosive ordnance, while already mentioned, is usually not, to my knowledge classed as "kinetic" nowadays as it distributes the force delivered in a very different manner from a traditional kinetic projectile.
Given that I've pointed out laser weapons are effectively a thermal weapon subclass, I guess non-laser thermals are obviously a thing that exists.
Chemical weapons are more or less viable too. In particular, biotech-based civilizations seem to enjoy corrosive chemical weapons in sci-fi.
Since I'm mentioning chemical weapons, how about biological ones? Not necessarily WMDs, maybe like short-lived beetles bred to bore holes into enemy starships' metal hulls or a dart gun that fires darts containing parasite eggs, which will turn enemies into mind-controlled drones after hatching.
Plasma weapons often appear in sci-fi as well, usually either as guns that fire clouds of glowy shit (if it's explained, it's usually described as highly agitated particles contained in a localized magnetic field or something of the sort), or as lightning guns.
Speaking of lightning guns, EMP weaponry has actually been the go to weapon type for humans in Matrix.
Aaand then if you want a world-shattering McGuffin, you can just rend reality asunder: teleportation tech has exciting and oft overlooked prospects as far as weaponizing it goes. It'll generally ignore armor unless it's bullshit unobtainium armor that specifically prevents this kind of weaponry with plot magic and it can basically remove parts of the enemy by just zapping them away.
Granted, in most titles those will only fill a supporting role of sorts, fleshing out the setting's weaponry selection but I figure I might as well mention whatever comes to mind.