Giants will win in my opinion. That's just purely on the basis of me thinking that the Giants defense will make a few big plays, and the Patriots' really won't.
But I dont' want to watch this year (but I probably will ugh). Giants v Patriots? Really? I'm in neither home market, so I could care less about a rematch, and would much rather have seen one of the defense/run teams in Ravens and Niners make it.