Murder.
A fraud charge, even if you're acquitted, can jeopardise your credit rating and future job prospects (especially any position of trust or involving money).
Being publicly declared a paedophile, even if you're later acquitted, can ruin your life, especially when applying for jobs or positions of of trust with children or vulnerable people.
Murder people can forgive, especially if it's a crime of passion as per the example given (in France it's not even considered to be as bad as proper murder).
Also, in the example given, once you're found to be innocent and someone else is convicted of the murder of your wife, you'd get a lot of sympathy for having lost your loved one, for having been falsely accused and having to endure the ordeal of the trial.
I'm pretty sure you'd be in a good position to seek compensation from the police and courts for actually being prosecuted for murder for 6 months on a handful of flimsy evidence, all the while the real murder went free for 6 months (in reality I doubt they'd even risk trying to prosecute you based on such weak evidence).
Harrison Ford's character in The Fugitive is a tragic hero figure, not a suspicious hate figure.
It's also worth considering when you apply for jobs in the public sector and/or any positions of trust, you have to declare any time you've been arrested, not just convicted, and I think fraud or child abuse would seem worse than murder (since it would be obvious to the employer it was a false arrest).
I once got arrested (and released less than a hour later) for 1 ecstasy tablet, but when I apply for jobs I have to declare I was arrested for "Possession of Class A Drugs" which appears 10 times worse on paper than the reality of the situation, which I'm sure affects my chances of getting a job even though it isn't supposed to.