I didn't know which one to pick, because the one I like the least is "the universe is teeming with life, a whole lot of it just as advanced as ours".
See, for each of your poll options, the reason we've never detected alien life is because none of it exists and/or wants to contact us. This is good, because the alternative is that alien life that gets as advanced as we've gotten happens a lot, but it always, or almost always, gets destroyed by something. This isn't necessarily cosmic horrors, so I wouldn't pick that poll option - it could be a high frequency of cosmic disasters, like gamma-ray-bursts, or it could be a very high probability for intelligent species to wipe themselves out right about now... or of course it could be just some... Thing. And the scariest part is we don't even know what the danger is, just that it's almost guaranteed to kill us all.
So yeah, your options don't come with that implied guarantee of extinction, so none of them are all that bad.