Well, technically, any multiplayer military shooter will at times have you killing American soldiers unless it is one of the few that don't feature America as one of the potential teams, but I guess multiplayer doesn't really count.Professor James said:I realized today that the only game that I think you can kill American soldiers in(outside of multiplayer) is Prototype, Grand Theft Auto V, and Saints Row the Third. I personally didn't feel bad and only fully realized what I did until later.
I guess the primary game I think of where you fight American soldiers would be Modern Warfare 2. The last few levels of that game have you fighting Shadow Company, which in the story is a group of American soldiers serving General Shepherd. While they are sort of borderline rogue, they are still technically part of the American military. However, they're more loyal to Shepherd than anyone else. Granted, at that point, it is unclear if the American government has even survived the invasion of the East Coast.