Barring FTL travel and instant communication: Missiles/Robots.
You have independent, very small tracking drones that use base-line interferometry over huge distances to gain enough resolution to target a ship from several light-seconds away, that guide missiles. They would likely be nuclear or purely ballistic, if your targetting and RCS is precise enough. That seems unlikely to be efficacious, so cluster munitions with nuclear payloads are most likely to kill your opponent with gamma-rays; near impossible to shield efficiently against and still maintain a sane mass/thrust ratio.
There's just no reliable way to hit something at any distance where relativity comes into play without active guidance, unless the target is relatively large and follows a predictable path (say, a planet). Getting close to an opponent would only be viable at known locations, such as a space station.
Space combat would involve firing complex sequences of missiles, since they would likely have to travel for days before hitting their targets, and the opponent would have plenty of time to fire countermeasures.
Any long-distance space combat is a MAD type scenario, so first-strike and interception is the only way you can "win".
Not exactly Star Wars, but that is a fantasy after all.
EDIT: BTW, I just did some handkerchief calculations, and those nuclear submunitions would have to be HUGE to reliably kill anything; say on the order of 100 submunitions each with a TNT equivalent of 100 megatons or more. Unless you have some pretty sofisticated AI in your missiles, I'd say alot more, like 1 gigaton per submunition. Even over relatively small distances on the astronomical scale, gamma radiation from a human-scale nuke isn't enough to reliably kill an opponent in a timely fashion. You don't wan't to wait for them to die a few days or weeks later, after they've fired their entire arsenal of similar or more powerful nukes....
You have independent, very small tracking drones that use base-line interferometry over huge distances to gain enough resolution to target a ship from several light-seconds away, that guide missiles. They would likely be nuclear or purely ballistic, if your targetting and RCS is precise enough. That seems unlikely to be efficacious, so cluster munitions with nuclear payloads are most likely to kill your opponent with gamma-rays; near impossible to shield efficiently against and still maintain a sane mass/thrust ratio.
There's just no reliable way to hit something at any distance where relativity comes into play without active guidance, unless the target is relatively large and follows a predictable path (say, a planet). Getting close to an opponent would only be viable at known locations, such as a space station.
Space combat would involve firing complex sequences of missiles, since they would likely have to travel for days before hitting their targets, and the opponent would have plenty of time to fire countermeasures.
Any long-distance space combat is a MAD type scenario, so first-strike and interception is the only way you can "win".
Not exactly Star Wars, but that is a fantasy after all.
EDIT: BTW, I just did some handkerchief calculations, and those nuclear submunitions would have to be HUGE to reliably kill anything; say on the order of 100 submunitions each with a TNT equivalent of 100 megatons or more. Unless you have some pretty sofisticated AI in your missiles, I'd say alot more, like 1 gigaton per submunition. Even over relatively small distances on the astronomical scale, gamma radiation from a human-scale nuke isn't enough to reliably kill an opponent in a timely fashion. You don't wan't to wait for them to die a few days or weeks later, after they've fired their entire arsenal of similar or more powerful nukes....