A lot of FPS games got me into learning to shoot. And apparently gave me a slight edge over my other family member when I was taken out to the range, since I knew (roughly) how to hold various weapons. (I dislike holding rifles, the way I can hold them comfortably makes them awkward to shoot and reload. Holding them effectively makes it hard to hold comfortably).
Bioshock was my first foray into Steampunk, which I still find more interesting than any other "standard" setting (Modern, medieval, cyberpunk, steampunk). Unless you count the intro of FF6 to be steampunk.
Guitar Hero introduced me to various bands
Lots of games (mostly RPGs), got me interested in various Mythologies.