somebody has probably already posted this but its a tie between
A) rabies - make you become mindless zombie killing machine
B) necrotizing fasciitis - eats you from the inside out and only way to stop it is to amputate.
HIV/Aids easily, you die a slow painful death and it's really easy to obtain, I have two friends who currently suffer from HIV so they still have a very slim chance, but the other two have aids and they're gone
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